Bone Form, Function, Injury, Regeneration, and Repair Alexia Hernandez-Soria Mathias Bostrom Bone form consists of its cellular morphology, matrix composition, and circulation. Bone function, regeneration, and repair integrate cellular and…
Principles of Orthopaedic Pharmacology Carol D. Morris Numerous orthopaedic conditions are amenable to pharmacologic intervention. This chapter will summarize the basic science principles behind the most commonly used drugs in…
Benign Soft Tissue Tumors Timothy A. Damron Gustavo De La Roza Benign soft tissue tumors outnumber soft tissue sarcomas by approximately 100:1. In adults, lipomas are the most common soft…
Biomaterials Joseph A. Spadaro Michael T. Clarke Julie M. Hasenwinkel The advances made in contemporary orthopaedic surgery are intimately related to the development of and use of implant biomaterials. These…
Cellular and Molecular Biology Matthew J. Allen The Cell Cycle The transformation from a fertilized egg to a complex multi-cellular organism, be it a mouse or a human, depends on…
Soft Tissue Sarcomas Carol D. Morris Soft tissue sarcomas are malignant neoplasms that arise in nonepithelial extraskeletal tissue (e.g., fat, muscle, fibrous structures, etc.) of mesenchymal origin. They account for…
Metabolic Bone Diseases Susan V. Bukata Metabolic bone diseases include a variety of diseases that affect the strength and overall quality of bones. Some of these diseases affect a huge…
Metastatic Disease Timothy A. Damron Metastatic disease to bone accounts for the largest number of bone lesions in patients greater than 40 years of age. In fact, the differential diagnosis…
Hematologic Malignancies Valerae O. Lewis Hematologic malignancies such as lymphoma and myeloma can manifest in bone, and these osseous manifestations can often be the first presentation of the systemic disease….
Werner Syndrome Kathryn Palomino Werner syndrome is a rare hereditary systemic disease, also known as adult progeria. It is characterized by signs of premature aging (gray hair, skin changes, and…
