Fig. 15.1 The blood capillary endothelium and the cellular-interstitial matrix are major barriers to efficient drug transport. When compared with the mesothelium, the interstitium and capillary barriers play greater roles…

Engineered T cells Target antigen Cancer Number of patients treated in trial Results Reference Year reported TCR-T gp100 Melanoma Sixteen One CR and two PR [29] 2009 MART-1/Melan-A Melanoma Thirty-one…

(1) The Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, People’s Republic of China   14.1 Physiological Drug…

Fig. 6.1 Trocar locations for laparoscopic gastrectomy (b) A monitor is located over the patient’s head, and the surgeon sits between patient’s legs for the procedure. First, the greater omentum…

and Baorui Liu1 (1) The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China   9.1 Introduction The…

Fig. 16.1 Various strategies for nanoparticle-based combinational drug delivery systems Recently, a great deal of interest has been focused on the application of combinational therapies in drug delivery systems [5]….

Fig. 12.1 The effects of chemotherapy and radiotherapy on the tumor microenvironment. A range of chemotherapeutic agents can affect the tumor microenvironment in a variety of ways. Oxaliplatin can induce…

Fig. 3.1 The intravasation and migration of CTC (Adapted from detection and clinical implications of circulating tumor cells (2015), Joosse SA et al. [1]) According to their biology characteristics, CTCs…

Fig. 7.1 Randomization scheme. R randomization, ECC epirubicin, cisplatin, capecitabine (Adapted from Neo-adjuvant chemotherapy followed by surgery and chemotherapy or by surgery and chemoradiotherapy for patients with resectable gastric cancer…