ONCOLOGY

Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation Oncology

Dec 25, 2017 by in ONCOLOGY Comments Off on Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation Oncology

© Springer International Publishing AG 2017Jeffrey Y.C. Wong, Timothy E. Schultheiss and Eric H. Radany (eds.)Advances in Radiation OncologyCancer Treatment and Research10.1007/978-3-319-53235-6_11 The Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation…

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and Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on and Radiotherapy

© Springer International Publishing AG 2017Jeffrey Y.C. Wong, Timothy E. Schultheiss and Eric H. Radany (eds.)Advances in Radiation OncologyCancer Treatment and Research10.1007/978-3-319-53235-6_10 Biomarkers and Radiotherapy Savita V. Dandapani1   (1) Department of Radiation Oncology, City of Hope, Duarte,…

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and the Treatment of Oligometastatic Disease

Dec 25, 2017 by in ONCOLOGY Comments Off on and the Treatment of Oligometastatic Disease

Publication Year Number of patients Median follow-up (months) RT dose Metastases control Overall survival University of Chicago (Wong et al. 2016) 2016 61 82 24–48 Gy in 3 fractions 44% at…

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Radiotherapy and Immunotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on Radiotherapy and Immunotherapy

Fig. 1 Ideally, drug combinations should shift the balance between the pro-immunogenic and immunosuppressive effects of radiotherapy to favor its pro-immunogenic effects and or abrogate the immune-suppressive ones. Multiple strategies in…

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Treatment of Acute Massive Pulmonary Embolism

Oct 25, 2017 by in ONCOLOGY Comments Off on Treatment of Acute Massive Pulmonary Embolism

Fig. 1a Dilated right ventricle in the setting of acute massive PE Fig. 1b Dilated right ventricle with large right atrial thrombi Fig. 1c Dilated right ventricle with large right…

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and von Willebrand Factor

Oct 25, 2017 by in ONCOLOGY Comments Off on and von Willebrand Factor

Fig. 1 VWF functions: After the platelets detect any defect in vascular wall, shear rate leads to the initial arrest and attachment of platelet at the site of injury. Shear-induced…

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Treatment of Thrombosis and Embolism

Oct 25, 2017 by in ONCOLOGY Comments Off on Treatment of Thrombosis and Embolism

Absolute contraindications: *Active internal bleeding or DIC *Recent cerebrovascular event (including TIA) *Recent neurosurgery or intracranial trauma (<3 months) *Absolute contraindication to anticoagulation Relative contraindications: *Recent CPR, major surgery, obstetrical…

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and Arterial Thrombosis: Is There a Link?

Oct 25, 2017 by in ONCOLOGY Comments Off on and Arterial Thrombosis: Is There a Link?

Fig. 1 Prevalence of carotid plaques in patients with unprovoked and secondary DVT and in the control subjects [8] Subsequently, three studies have provided further evidence in support of the…

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Diagnosis of Pulmonary Embolism

Oct 25, 2017 by in ONCOLOGY Comments Off on Diagnosis of Pulmonary Embolism

Fig. 1 Planar perfusion scintigraphy in anterior-posterior projection showing a classic segmental wedge-shaped perfusion defect Only a few years after the introduction of perfusion scintigraphy supplemental ventilation scintigraphy was introduced…

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