New Trials
Study Type of study Phase Time Drug Id number* Country Feasibility Study of HIPEC for Patients With Stage III or Only Pleural Stage IV Ovarian Carcinoma in First-Line Therapy Safety/efficacy…
ONCOLOGY
Main Topics of Discussion and New Trends
Fig. Peritoneal Cancer Index (PCI) classification: Three-dimensional imaging simulation for PCI mapping and scoring. An imaging database can furnish all useful images to place the lesions; dedicated software calculates overall…
Palliative Treatments
Study [Reference] No. (PSM origin) Drugs Operative time (min) HIPEC duration (min) Hospital stay (days) Mortality Morbidity Ascites resolution Median survival (months) Chang et al. 2001 [33] 2 (1 MPM,…
The Role of Surgery
Fig. 11.1 Peritoneal Cancer Index (PCI) scoring system 11.4 Defining Completeness of Cytoreduction: CC score Completeness of cytoreduction is the most important prognostic factor after CRS. Residual disease after CRS…
Epidemiology: Extent of the Problem
Year 2012 Description Age 0–44 45–54 55–64 65–74 75+ Total Malignant neoplasm of peritoneum or retroperitoneum (primary) 133 264 518 665 732 2,312 Malignant neoplasm of peritoneum or retroperitoneum (secondary)…
Organizational Problems, Costs, and Data Collection
Procedural safety recommendations Surgical field Use of disposable drapes (not textile cloth) Operating room Closed door, access restriction, prevent of possible spills Caregivers Disposable impervious gown and shoe covers; double…
Morbidity and Mortality
Grade I: Events carrying minor risks; complication, if left untreated, resolves spontaneously or at most requires a simple bedside procedure. Analgesics, antipyretics, antiemetics, antibiotics orally, and antidiarrheals are permitted Grade…
The Role of Systemic Chemotherapy
34. Helm CW, Randall-Whitis L, Martin RS et al (2007) Hyperthermic intraperitoneal chemotherapy in conjunction with surgery for the treatment of recurrent ovarian carcinoma. Gynecol Oncol 105:90–96CrossRefPubMed 35. Cotte E,…
Mechanism of Intraperitoneal Spread of Free Cancer Cells
Fig. 3.1 Cellular pathology of peritoneal invasion and colonization and molecular pathways 3.3.1 Loss of Cell Adhesion and Increased Motility After detachment from the primary cancer, free tumor cells show…
Peritoneal Surface Malignancies
Malignant Borderline/low grade Primary DMPM (Diffuse Malignant WDPM Peritoneal Mesothelioma) (Well-differentiated Papillary Mesothelioma); MPM (Multicystic Peritoneal Mesothelioma) PPSPC (Primary Peritoneal Serous Papillary Carcinoma) DSRCT (Desmoplastic Small Round Cell Tumor) …
