Type Characteristic Mechanism Examples Type A Dose-dependent Chemotherapy-induced myelosuppression Predictable Type B Dose-independent Nonimmune-mediated Primaquine-induced hemolytic anemia, metformin-induced megaloblastic anemia, methotrexate-induced megaloblastic anemia, clozapine-induced neutropenia Unpredictable Immune-mediated IgG-mediated cytotoxicity (type…
Heavy metals Arsenic compounds, gold, mercurial diuretics Analgesics and NSAID Acid acetylsalicylic, aminopyrine, benoxaprofen, diclofenac, diflunisal, dipyrone, fenoprofen, indomethacin,ibuprofen,phenylbutazone, piroxicam, sulindac, tenoxicam, tolmetin Antipsychotics, sedatives, antidepressants Amoxapine, chlordiazepoxide, clozapine, diazepam,…
Fig. 6.1 Diagnostic algorithm based on blood smear (Adapted from Stasi [3]) “True” thrombocytopenia, to a variable degree, affects all types of ICU patients in all parts of the world;…
© Springer-Verlag Italia 2015Giorgio Berlot and Gabriele Pozzato (eds.)Hematologic Problems in the Critically Ill10.1007/978-88-470-5301-4_1 1. Introduction Giorgio Berlot1 and Gabriele Pozzato2 (1) Anesthesia and Intensive Care, University of Trieste, University Hospital, Trieste, Italy (2) Haematology, University of…
Fig. 48.1 This patient got a diagnosis of “Klippel–Trenaunay–Weber syndrome” when she was 3. As she was told that this is an untreatable disease and because she was free of…
Fig. 46.1 Characteristic venous malformations on the sole of the foot of a blue rubber bleb nevus syndrome (BRBNS) patient. This skin manifestation on the sole of the foot is…
Fig. 41.1 (a) Focal airway infantile hemangioma of the left subglottis. (i) Initial presentation (ii) and (iii) after two CO2 laser procedures. (b) Focal airway infantile hemangioma of right subglottis….
Fig. 35.1 Therapeutic algorithm of vascular malformations. Only the simple form of port-wine stain does not need any further diagnostics. In all other cases, the visible part of the vascular…
Fig. 49.1 (a, b) Extratruncular and truncular LM (a) depicts a typical “extratruncular” lymphatic malformation (LM) lesion presenting as a localized swelling along the right neck extended to the submandibular…
Fig. 47.1 3D CT demonstrating a congenital fusiform Congenital fusiform right iliac aneurysm, involving common and hypogastric artery. Asymptomatic patient Venous truncular defects are more common. Aplasia of the inferior…
