1 is most favorable and 10 least favorablePlease rate your fatigue (weariness, tiredness) by circling the one number that best describes your worst level of fatigue during past 24 hoursa(No…
Figure 13.1 Diagnostic algorithm for hypereosinophilia and treatment options based on each subtype. FISH, fluorescent in situ hybridization; RT-PCR, reverse transcriptase polymerase chain reaction; NOS, not otherwise specified; WHO, World…
Manage scenarios associated with increased risk, e.g., surgery, pregnancy The most important direct way of assessing compliance is through patient interview.2 Other measures, such as direct observation of medication intake,…
(pending WHO endorsement) Major criteria1. Hb >18.5 g/dL in men, >16.5 g/dL in women, or evidence of increased red cell volume, ora1. Hb >16.5 g/dL in men, > 16.0 g/dL…
Figure 7.1 Flow chart of recommendations for the management of patients with essential thrombocythemia (ET). CV, cardiovascular; HU, hydroxyurea; WHO, World Health Organization. Intervention on lifestyle Thrombosis is a multifactorial…
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a low circulating platelet count caused by destruction of antibody-sensitized platelets in the reticuloendothelial system. ITP can be classified as…
Hydroxyurea therapy offers promise for ameliorating the clinical course of children with sickle cell disease (SCD). Hydroxyurea is a prototypic therapeutic option; it can be administered with minimal side effects,…
This article describes recent clinical and research advances in hemophilia therapy. Different prophylactic regimens for the management of severe hemophilia are described along with the use of adjuvant treatment options…
β-Thalassemia, originally named Cooley anemia, is an inherited blood disease. Various types of thalassemia are inherited anemias caused by mutations at the globin gene loci on chromosomes 16 and 11,…
Effective chelation therapy can prevent or reverse organ toxicity related to iron overload, yet cardiac complications and premature death continue to occur, largely related to difficulties with compliance in patients…
