ENDOCRINOLOGY

Mediastinal/Thoracoscopic Parathyroidectomy

Jul 14, 2017 by in ENDOCRINOLOGY Comments Off on Mediastinal/Thoracoscopic Parathyroidectomy

Figure 5.1 Sestamibi scan showing persistent uptake of the radionuclide by an intrathoracic parathyroid adenoma (arrow) Figure 5.2 CT scan confirming the presence of a parathyroid adenoma in the mediastinum…

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Substernal Goiter

Jul 14, 2017 by in ENDOCRINOLOGY Comments Off on Substernal Goiter

Figure 8.1 The upper pole is prepared and resected with ligation of the superior thyroid artery and vein Figure 8.2 The superior parathyroid gland and the recurrent laryngeal nerve (RLN)…

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Parathyroid Transplantation

Jul 14, 2017 by in ENDOCRINOLOGY Comments Off on Parathyroid Transplantation

Figure 4.1 The parathyroid gland is grasped along its long axis (shown here with DeBakey forceps) and, using a scalpel with a #10 Bard Parker blade, whole tissue discs approximately…

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Effects of Prior Cushing’s Syndrome

Jun 27, 2017 by in ENDOCRINOLOGY Comments Off on Effects of Prior Cushing’s Syndrome

Fig. 1 Main clinical manifestations after remission of Cushing’s syndrome This chapter addresses current information on the main long-term/persistent effects of prior Cushing’s disease/glucocorticoid exposure. Cardiovascular and Metabolic Comorbidities Hypercortisolism…

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Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

Jun 27, 2017 by in ENDOCRINOLOGY Comments Off on Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

Target tissue Glucocorticoid hypersensitivity = Glucocorticoid excess Glucocorticoid resistance = Glucocorticoid deficiency Central nervous system Insomnia, anxiety, depression, defective cognition Fatigue, somnolence, malaise, defective cognition Liver + Gluconeogenesis, + lipogenesis…

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