Central Hypothyroidism
June 2008 April 2010 June 2010 August 2010, LT4 1.0 μg/kg bw/day December 2010, LT4 1.4 μg/kg bw/day PRL, ng/ml (n.v. 3–20) 31 Basal: 41 +60’: 34 PRL recovery…
ENDOCRINOLOGY
Acromegaly, Awareness Is Paramount for Early Diagnosis: Highlights of Diagnosis and Treatment Challenges
Fig. 2.1 Contrast-enhanced T1-weighted coronal and sagittal MR images; preoperative and 3 months postoperative Why Does Acromegaly Fail to Be Diagnosed for Years? Growth hormone (GH) is the most abundant…
Introduction
Organ system Manifestations Cardiovascular Bradycardia, heart failure, pericardial effusion CNS Depression, fatigue, cognitive dysfunction, myxedema coma Hematopoietic Macrocytic anemia, target cells Metabolic Hyperlipidemia, weight gain Musculoskeletal Arthralgias, myositis Gastrointestinal Constipation…
Exogenous Thyrotoxicosis
Intentional Inadvertent 1. Iatrogenic (a) Suppressive thyroxine dose in thyroid cancer (b) Excessive thyroxine dose to shrink goiter (c) Patient’s insistence on higher thyroid hormone dose 2. Factitious (a) Surreptitious ingestion of thyroid hormone to feign…
Introduction
Fig. 1.1 Adapted from Neurosurg Focus 29(4):E15, Fleseriu, M., Delashaw, J.B., and Cook, D.M. Acromegaly: a review of current medical therapy and new drugs on the horizon, page 3, Copyright…
TSH-Secreting Pituitary Adenoma
Fig. 6.1 Pituitary macroadenoma (arrows) abutting the optic chiasm superiorly on contrast-enhanced coronal (a) and sagital (b) MRIs Other evaluations during his hospitalization revealed evidence of cardiomyopathy that was attributed…
Introduction
© Springer Science+Business Media New York 2015Terry F. Davies (ed.)A Case-Based Guide to Clinical Endocrinology10.1007/978-1-4939-2059-4_5 5. Introduction David S. Cooper1 (1) Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, 1830 E. Monument…
Endocrine Tumors of the Pancreas
Endocrine Tumors of the Pancreas Maha T. Barakat Houman Ashrafian Stephen R. Bloom Pancreatic endocrine tumors make up only 1% to 2% of all tumors of the pancreas but form…
Hypoglycemia
Hypoglycemia Benjamin Glaser Gil Leibowitz Hypoglycemia, simply defined as a low blood glucose level, is a laboratory finding that may or may not be associated with significant pathology. Pathologic hypoglycemia…
Diabetes Mellitus and Wound Healing
Diabetes Mellitus and Wound Healing Parham A. Ganchi Elof Eriksson Diabetes mellitus, the most common endocrine disease, is a complex systemic disorder with a broad range of effects on nearly…
