Hypothyroidism in Infants, Children, and Adolescents: Acquired Hypothyroidism Guy Van Vliet Johnny Deladoëy The unique feature of hypothyroidism in infants, children, or adolescents is that, if the diagnosis is delayed,…
Hypothyroidism in Infants and Children: Congenital Hypothyroidism Guy Van Vliet Johnny Deladoëy A relationship between an absent or defective thyroid gland and mental retardation was recognized long ago, but the…
Hypothyroidism in Infants and Children: Neonatal Screening Guy Van Vliet Johnny Deladoëy Neonatal Screening Population-based biochemical screening of newborn infants for congenital hypothyroidism became possible in the 1970s after the…
The Maturation of Thyroid Function in the Perinatal Period and During Childhood Delbert A. Fisher Rosalind S. Brown Introduction The maturation of thyroid function in the human fetus is a…
Anaplastic Thyroid Cancer and Miscellaneous Tumors of the Thyroid Joshua P. Klopper Madeleine A. Kane Bryan R. Haugen Introduction The vast majority of thyroid cancers are follicular cell–derived, well-differentiated tumors…
Medullary Thyroid Carcinoma Mimi I. Hu Camilo Jimenez Gilbert J. Cote Robert F. Gagel Introduction Medullary thyroid carcinoma (MTC) is an uncommon malignant tumor derived from the C or calcitonin…
Medical Management of Differentiated Epithelial Cell Thyroid Cancer Sebastiano Filetti R. Michael Tuttle Steven I. Sherman The medical management of patients with differentiated thyroid cancer (DTC) begins following completion of…
Staging and Prognosis of Differentiated Thyroid Cancer Richard T. Kloos Introduction In the United States, the 10-year overall relative survival rates for patients with papillary thyroid cancer (PTC), follicular thyroid…
Carcinoma of the Follicular Epithelium: Surgical Therapy Gregory W. Randolph Gerard M. Doherty Introduction The management strategy for follicular cell-derived thyroid carcinoma includes operation for nearly all patients, as well…
Molecular Genetics of Tumors of Thyroid Follicular Cells James A. Fagin Yuri Efimovich Nikiforov Thyroid follicular cells give rise to tumors with distinct pathologic and clinical features. Follicular cell-derived cancers…
