Overview of Basic Coagulation and Fibrinolysis
Overview of Basic Coagulation and Fibrinolysis Gilbert C.White II Victor J. Marder Sam Schulman William C. Aird Joel S. Bennett The development of a fibrin clot occurs after a series…
Biostatistics and Epidemiology: The Basic Science of Clinical Research
Biostatistics and Epidemiology: The Basic Science of Clinical Research Kerry L. Lee In the basic sciences, there is an essential knowledge base and an array of tools and techniques that…
Overview of the Immune System
Overview of the Immune System Andrew H. Lichtman The immune system is a complex collection of molecules, cells, tissues, and organs whose major function is to protect hosts from microbial…
Cell Biology, Protein Processing, and Cell Signaling
Cell Biology, Protein Processing, and Cell Signaling Randal J. Kaufman Laura Popolo In order to perform their multiple functions, eukaryotic cells have evolved an internal structural organization that consists of…
Coagulation Enzymology
Coagulation Enzymology Sriram Krishnaswamy THE CONTEXT Blood coagulation is initiated by the exposure of tissue factor to flowing blood following vascular damage.1,2 A series of highly specific proteolytic activation steps…
Molecular and Clinical Genetics
Molecular and Clinical Genetics Lesley Everett Karl Desch David Ginsburg Keeping up to date with the remarkable progress in human genetics and the rapidly changing genomic laboratory toolbox poses a…
Molecular Evolution of the Vertebrate Blood Coagulation System
Molecular Evolution of the Vertebrate Blood Coagulation System Marianne A. Grant William C. Aird Most multicellular organisms have evolved hemostatic mechanisms to prevent the loss of fluid and promote blood…
The Field of Hemostasis and Thrombosis: Selected Translational Achievements
The Field of Hemostasis and Thrombosis: Selected Translational Achievements Victor J. Marder William C. Aird Joel S. Bennett Sam Schulman Gilbert C. White II INTRODUCTION As with any field of…
General Principles and Management
General Principles and Management Bruce J. Davidson Kenneth A. Newkirk Kenneth D. Burman THYROID CANCER Introduction Epidemiology—Increasing Incidence of Thyroid Cancer. According to cancer statistics, there has been a substantial…
Systemic Targeted Therapy for Recurrent and Metastatic Head and Neck Squamous Cell Cancer
Systemic Targeted Therapy for Recurrent and Metastatic Head and Neck Squamous Cell Cancer Matthew G. Fury David G. Pfister This chapter reviews chemotherapy options for patients with recurrent and metastatic…
