Factor XIII
Factor XIII CéDric Duval Helen Phiuppou Robert A.S. AriëNs Factor XIII (FXIII) is an unusual blood coagulation factor, circulating as a heterotetramer composed of two catalytic A-subunits and two noncatalytic…
Fibrinogen Structure and Function
Fibrinogen Structure and Function John W. Weisel Carl-Erik H. Dempfle Fibrinogen, originally factor I (FI) in the clotting cascade, is a fibrous adhesive glycoprotein, present in the plasma at a…
The Factor XII-Driven Plasma Contact System
The Factor XII-Driven Plasma Contact System Thomas RennÉ SUMMARY The contact system is a protease cascade that is initiated by coagulation factor XII activation and operates on cardiovascular cells. The…
Structure and Function of Vitamin K-Dependent Coagulant and Anticoagulant Proteins
Structure and Function of Vitamin K-Dependent Coagulant and Anticoagulant Proteins Kanagasabai Vadivel Amy E. Schmidt Victor J. Marder Sriram Krishnaswamy S. Paul Bajaj Physiologic coagulation is initiated when, upon vascular…
Structure and Function of von Willebrand Factor
Structure and Function of von Willebrand Factor Sandra L. Haberichter Robert R. Montgomery von Willebrand disease (vWD) is the most common hereditary bleeding disorder with a prevalence estimated by some…
Factor V and Factor VIII
Factor V and Factor VIII Randal J. Kaufman Philip J. Fay Laura Popolo Thomas L. Ortel Factor V and factor VIII are two homologous nonenzymatic proteins that play a critical…
Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation
Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation James H. Morrissey George J. Broze Jr. Blood circulates as a liquid, but once it escapes from an injured blood…
Genetics of Coagulation
Genetics of Coagulation Rodney M. Camire Paris Margaritis The determination of the gene, complementary deoxyribonucleic acid (cDNA), and amino acid sequences of all of the proteins known to be involved…
The Blood Coagulation Factors and Inhibitors: Their Primary Structure, Complementary DNAs, Genes, and Expression
The Blood Coagulation Factors and Inhibitors: Their Primary Structure, Complementary DNAs, Genes, and Expression Dominic W. Chung Wenfeng Xu Earl W. Davie A BRIEF INTRODUCTION TO THE BLOOD COAGULATION CASCADE…
