Immunoglobulins: Structure and Function
Immunoglobulins: Structure and Function Harry W. Schroeder Jr David Wald Neil S. Greenspan INTRODUCTION Immunoglobulins (Igs) are marked by a duality of structure and function.1 In common with other members…
Evolution of the Immune System
Evolution of the Immune System Martin F. Flajnik Louis Du Pasquier INTRODUCTION Defense mechanisms are found in all living things, even bacteria, where they are surprisingly elaborate. Although new adaptive…
Lymphoid Tissues and Organs
Lymphoid Tissues and Organs Eitan M. Akirav Noelia Alonso-Gonzalez Lucy A. Truman Nancy H. Ruddle INTRODUCTION The mammalian immune system defends against invading pathogens, by both the innate and adaptive…
History of Immunology
History of Immunology Steven Greenberg INTRODUCTION There comes a time during every argument at which the two opposing parties reach a critical juncture: either resolution or impasse. Variations on this…
The Immune System
The Immune System William E. Paul The immune system is a remarkable defense mechanism. It makes rapid, specific, and protective responses against the myriad potentially pathogenic microorganisms that inhabit the…
Cancer of the Testis
Cancer of the Testis Lance C. Pagliaro Christopher J. Logothetis INTRODUCTION Testicular cancers are the most common malignant neoplasm affecting men ages 15 to 35 years. Approximately 90% of testicular…
Cancer of the Urethra and Penis
Cancer of the Urethra and Penis Edouard J. Trabulsi Leonard G. Gomella INTRODUCTION Penile and urethral carcinomas are uncommon malignancies, with a peak incidence in the 6th decade of life….
Cancer of the Prostate
Cancer of the Prostate Howard I. Scher Peter T. Scardino Michael J. Zelefsky INTRODUCTION The approach to prostate cancer diagnosis and treatment has changed dramatically across the spectrum of the…
Molecular Biology of Prostate Cancer
Molecular Biology of Prostate Cancer Felix Y. Feng Arul M. Chinnaiyan Edwin M. Posadas INTRODUCTION Prostate cancer is the most common malignancy and the second leading cause of cancer death…
Cancer of the Bladder, Ureter, and Renal Pelvis
Cancer of the Bladder, Ureter, and Renal Pelvis Adam S. Feldman Jason A. Efstathiou Richard J. Lee Douglas M. Dahl M. Dror Michaelson Anthony L. Zietman INTRODUCTION This chapter details…
