Measurement of Lipids, Lipoproteins, and Apolipoproteins Paul S. Bachorik The concentrations of the plasma lipoproteins strongly predict the development of cardiovascular disease (CVD) and are used to evaluate the dyslipoproteinemias…
Lipid, Apolipoprotein, and Lipoprotein Metabolism: Implications for the Diagnosis and Treatment of Dyslipidemia Peter O. Kwiterovich Jr. Human plasma lipoprotein metabolism is complex. An understanding of normal lipid, apolipoprotein, and…
TREATMENT OF OBESITY Part of “CHAPTER 126 – OBESITY“ WEIGHT-REDUCTION MEASURES In most obese individuals, specific aberrations of the weight-control mechanism described under Pathogenesis cannot be identified and, thus, treatment…
ENDOCRINE AND METABOLIC CONSEQUENCES OF OBESITY Part of “CHAPTER 126 – OBESITY“ Various alterations in endocrine and metabolic function can be observed in obese individuals, including disturbances of growth hormone,…
ADIPOSE TISSUE GROWTH AND DEVELOPMENT Part of “CHAPTER 126 – OBESITY“ EARLY GROWTH OF ADIPOSE TISSUE Normal growth of human adipose tissue is achieved through an increase in adipocyte size…
PATHOGENESIS Part of “CHAPTER 126 – OBESITY“ THERMODYNAMIC CONSIDERATIONS It has become customary to remind all who deal with obesity that it is a disease of energy storage and as…
DEFINITION AND COMPLICATIONS OF OBESITY Part of “CHAPTER 126 – OBESITY“ DETERMINATION OF OBESITY Obesity is an excess of body fat (adipose tissue), and ideally the diagnosis should be based…
PREVALENCE OF OBESITY Part of “CHAPTER 126 – OBESITY“ An expert panel assembled by the National Institutes of Health (NIH) stated, “An estimated 97 million adults in the United States…
CLINICAL ABNORMALITIES OF APPETITE Part of “CHAPTER 125 – APPETITE“ KLEINE-LEVIN SYNDROME The Kleine-Levin syndrome (see Chap. 128) is a rare disease comprising periodic hypersomnia, hyperphagia, and abnormal behavior frequently…
