Modifications to Blood Components
Blood component modifications can be performed by the hospital blood bank for select clinical indications. In general, modification of blood components increases costs and may delay availability of the blood…
Transfusion Reactions
Transfusion reactions are common occurrences, and clinicians who order or transfuse blood components need to be able to recognize adverse sequelae of transfusion. The differential diagnosis of any untoward clinical…
Pathogen Inactivation Technologies
Pathogen inactivation technologies represent a shift in blood safety from a reactive approach to a proactive protective strategy. Commercially available technologies demonstrate effective killing of most viruses, bacteria, and parasites…
Management of Patients with Sickle Cell Disease Using Transfusion Therapy
Red blood cell (RBC) transfusion therapy is a key component of comprehensive management of patients with sickle cell disease (SCD) and has increased over time as a means of primary…
Platelet Transfusions in Patients with Hypoproliferative Thrombocytopenia
Patients with hematologic malignancies frequently become thrombocytopenic as a result of their underlying malignancy or treatments, including cytotoxic chemotherapy and hematopoietic stem cell transplantation and are at increased risk of…
Imaging of Bone Marrow
Bone marrow is the essential for function of hematopoiesis, which is vital for the normal functioning of the body. Bone marrow disorders or dysfunctions may be evaluated by blood workup,…
Imaging of Spinal Manifestations of Hematological Disorders
Imaging manifestations of hematological diseases and their potential complications are broad, and there may be significant overlap in features of various disease processes. Knowledge of appropriate choice of imaging test,…
Central Nervous System Complications of Oncologic Therapy
Traditional and newer agents used to treat cancer can cause significant toxicity to the central nervous system. MRI of the brain and spine is the imaging modality of choice for…
Central Nervous System Complications of Hematopoietic Stem Cell Transplant
Hematopoietic stem cell transplantation (SCT) is now commonly used to treat several hematologic and nonhematologic diseases. Central nervous system (CNS) complications post-transplantation occur commonly in the first year and result…
Venous Thrombosis
Cerebral venous sinus thrombosis is an elusive diagnosis with profound potential neurologic consequences. Although there are numerous reported predisposing conditions, by far the most common is a prothrombotic hypercoagulable state….
