Fig. 3.1 Cellular pathology of peritoneal invasion and colonization and molecular pathways 3.3.1 Loss of Cell Adhesion and Increased Motility After detachment from the primary cancer, free tumor cells show…
Malignant Borderline/low grade Primary DMPM (Diffuse Malignant WDPM Peritoneal Mesothelioma) (Well-differentiated Papillary Mesothelioma); MPM (Multicystic Peritoneal Mesothelioma) PPSPC (Primary Peritoneal Serous Papillary Carcinoma) DSRCT (Desmoplastic Small Round Cell Tumor) …
Nation Year approved Reference France 2003 [3] Holland 2003 [4] Germany 2010 [5] Spain 2012 [6] United Kingdom 2013 [7] In the United States, the National Comprehensive Cancer Network guidelines…
Fig. 2.1 Mammogram showing microcalcifications under nipple in a 45-year-old patient with ductal carcinoma in situ In some centers, even patients with locally advanced breast cancer are considered eligible for…
Fig. 7.1 Images demonstrating various forms of radiation injury affecting breast reconstruction. (a) Acute diffuse radiation injury characterized by erythema, edema, and desquamation of injured skin. (b) Fibrotic soft tissue…
Fig. 6.1 Breast ultrasound prior to placement of cryoablation probe (Courtesy of Dr. Rosa Hwang) Fig. 6.2 Cryoablation probe inserted with ultrasound guidance through the center of the tumor with…
Fig. 1.1 Breast tissue patterns according to the fifth edition of the BIRADS lexicon. (a) Predominantly fatty, (b) scattered fibroglandular, (c) heterogeneously dense, and (d) extremely dense At present, although…
LRR (10 years) Any first recurrence (10 years) Breast cancer mortality (20 years) No RT RT Abs No RT RT Abs No RT RT Abs N = 1314, 1–3+ ALN 20.3 3.8 16.5 45.7…
Hormone receptor-positive/HER2-negative HER2-positive Triple-negative CDK inhibitors Palbociclib with bazedoxifene in HR-positive breast cancer NCT02448771 CDK4/CDK6 inhibitor, ribociclib (LEE011), in combination with trastuzumab or T-DM1 for HER2-positive advanced/MBC NCT02657343 Palbociclib…
Fig. 8.1 (a) Flat epithelial atypia (FEA ) (b) Atypical ductal hyperplasia (ADH ) The immediate question a clinician faces when a patient is diagnosed with pure FEA on core…
