© Springer International Publishing Switzerland 2016Aamir Ahmad and Shirish Gadgeel (eds.)Lung Cancer and Personalized MedicineAdvances in Experimental Medicine and Biology89310.1007/978-3-319-24223-1_9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer Sai-Hong Ignatius Ou1 and Keisuke Shirai2 (1) Chao Family…
Fig. 1 Ways to leave your EGFR inhibitor: biochemical pathways leading to resistance to small molecule EGFR drugs such as gefitinib and erlotinib. (a) Structures of two approved EGFR TKIs,…
Fig. 1 Vascular endothelial growth factor receptor signal transduction (Reprinted with permission from Roskoski. CROH 2007 62(3):179–213) The role of serum VEGF (VEGF-A) in tumor growth and development has been…
Parameter Group EO EC BF R (mm) Controls 2.0 1.9 2.3 #,$ (1.7–2.6) (1.6–2.6) (1.8–2.8) OA 2.7** 2.8*** 3.2***,## (2.4–3.4) (2.2–3.8) (2.5–4.1) RA 2.6** 2.8** 3.3***,###,$$ (2.1–3.4) (2.1–3.4) (2.7–4.1) A…
Fig. 1 Decreased Cath V (a), increased endostatin (b) and IL-18 (c) in BALF of Besnier-Boeck-Schaumann disease (BBS) patients as compared with healthy volunteers ROC curves for Cath V, endostatin,…
Fig. 1 Serum concentrations of thrombospondin-2 (TSP-2) (a) and of fibroblast growth factor-2 (FGF-2) (b) in non-small cell lung cancer (NSCLC) patients and healthy control subjects We constructed ROC curves…
Fig. 1 Clinical characteristics of patients with Hashimoto’s thyroiditis 3.2 Physical Examination and Ultrasound The most frequent finding in HT children was a firm thyroid gland on palpation: in 44…
Alleles Exposed n (%) Controls n (%) OR (95 %CI) p χ2 XPD Lys 63 (63 %) 106 (77 %) Ref. Gln 37 (37 %) 32 (23 %) 1.94 (1.10–3.43) 0.015 – XPC Lys…
Rapid progression (n = 54) Slow progression (n = 55) p Age at examination (years) 14.6 ± 7.5 16.5 ± 5.1 NS (0.7–24.0) (7.3–25.0) NS Age at CKD diagnosis (years) 9.9 ± 6.8 5.6 ± 6.1 0.001 (0.01–22.0) (0.1–20.0) Etiology of…
Sarcoidosis Controls p (n = 111) (n = 65) Age (years) 44.8 ± 10.4 43.3 ± 12.4 BMI (kg/m2) 28.2 ± 3.9 26.8 ± 5.6 0.091 FAS 22.9 ± 7.9 17.0 ± 3.3 0.046 MRC 1.3 ± 0.8 1.1 ± 0.3 0.028 OCD 1.6 ± 0.8 1.1 ± 0.3 0.025 Borg’s scale 0.7 ± 1.3…
