The Endocrinology of Sexual Behavior and Gender Identity
Chapter 124 The Endocrinology of Sexual Behavior and Gender Identity Louis J. Gooren Prenatal, Postnatal, and Childhood Years Sexual Differentiation Brain Sexual Differentiation Disorders of Sexual Differentiation Complete Androgen Insensitivity…
Glucagon and the Glucagon-Like Peptides
FIGURE 35-1. Structure of proglucagon and the proglucagon-derived peptides. The amino acid sequences of glucagon, glucagon-like peptide (GLP)-1, and GLP-2 are shown, as well as the cleavage site for dipeptidyl…
Control of Hormone Secretion
FIGURE 3-1. Schematic diagram of the anterograde secretory pathway in a peptide hormone–secreting endocrine cell. Secretory proteins synthesized in the endoplasmic reticulum (ER) are transported to and through Golgi stacks…
Classification and Diagnosis of Diabetes Mellitus
Neonatal diabetes is rare and may be transient or permanent.37 Several genetic defects have been identified in these patients, most notably mutations in the adenosine triphosphate (ATP)-sensitive potassium channel (KATP)…
Hypothalamic Syndromes
FIGURE 12-1. Schematic representation of lateral brain section demonstrating hypothalamic nuclei. Dashed lines represent the frontal (coronal) section planes illustrated in Figures 12-2 and 12-3. 1, preoptic nucleus; 2, paraventricular…
Anorexia Nervosa, Bulimia Nervosa, and Other Eating Disorders
FIGURE 30-1. Extreme cachexia in an anorexia nervosa patient. (From Bliss EL, Branch CHH: Anorexia Nervosa: Its History, Psychology, and Biology. New York: Paul B. Hoeber, 1960.) A corollary of…
Control of Hormone Gene Expression
FIGURE 2-1. Chemical structure of DNA and its relationship to chromatin. The most basic unit of the chromosome is DNA, which is composed of polynucleotide chains made up of four…
Hyperglycemia Secondary to Nondiabetic Conditions and Therapies
Possible mechanisms by which pancreatic cancer could contribute to the development of type 2 diabetes include the following: (1) destruction of islets, (2) impairment of the insulin secretory mechanism, (3)…
