Hyperparathyroidism in MEN2 Syndromes
ret codon A/A change in MEN2 syndromes ATA risk level Primary hyperparathyroidism C609F/R/G/S/Y B C611R/G/F/S/W/Y B C618R/G/F/S/Y B C620R/G/F/S/W/Y B C630R/F/S/Y B Rare D631Y B Rare 633/9 base pair duplication…
as Biomarker for the Medullary Thyroid Carcinoma
Fig. 1 Organization of the calcitonin/calcitonin gene-related peptide gene and its peptide hormone products. CTN calcitonin, CGRP calcitonin gene-related peptide, KC katacalcin, SP signal peptide, K lysine, R arginine, G glycine,…
Medullary Thyroid Cancer Genotype–Phenotype Correlation
MTC risk group Exon Codon Recommended age for genetic testing Highest risk 16 918 As soon as possible (first year of life) High-risk 11 634 3 years 15 883 3…
The Spleen and Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 5.1 Introduction The word spleen comes from the Greek σπλήν (splḗn) and is the idiomatic equivalent of…
Musculoskeletal Manifestations of Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 8.1 Introduction One of the common manifestations of sickle cell anemia is vaso-occlusive crises which affect virtually…
Hepatobiliary Complications of Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 6.1 Introduction SCA can affect any part of the body and poses diagnostic and therapeutic dilemmas to…
Genetics and Pathophysiology of Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 2.1 Introduction The normal hemoglobin is made up of two parts, heme and protein. The protein is…
The Acute Chest Syndrome in Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 7.1 Introduction Acute chest syndrome (ACS) is defined as a new infiltrate on chest X-ray that is…
Clinical Features of Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia 4.1 Introduction Sickle cell anemia (SCA) is an autosomal recessive disorder that results from an abnormal gene…
History of Sickle Cell Anemia
(1) Department of Surgery, Dar A lAlafia Medical Company, Qatif, Saudi Arabia Sickle cell anemia is an inherited disease that existed in Africa for at least 5000 years but…
