Fig. 2.1 Immunohistochemistry demonstrates basal cells (stained brown with marker 34betaE12) in benign glands, while the surrounding malignant glands are negative 2.3 Immunohistochemistry The immunostains commonly used are p63 (nuclear…
Fig. 6.1 After ligand binding to PSMA the ligand-PSMA complex is internalized, resulting in an effective accumulation of the bound molecule in tumor cells 6.1 Diagnostic Application Based on the…
Low-risk prostate cancer All of T1 or T2a, Gleason < 7, PSA < 10 Intermediate-risk prostate cancer Between low- and high-risk groups High-risk prostate cancer Any of T3 or T4, Gleason > 7, PSA > 20 In general…
Fig. 4.1 Shows the comparison between a conventional PET detector (a) and the depth-of-interaction (DOI) detector (b). The DOI detector eliminates the parallax error, caused by the thickness of the…
Fig. 8.1 Mini Deluxe Phantom tested by UIH PET/CT scanner Fig. 8.2 Hoffman brain phantom tested by UIH PET/CT scanner 8.2 Animal Study Animal studies were applied to focus on…
Fig. 7.1 Immunohistochemistry (IHC) of murine testis. (a) Antibody-specific staining of a protein antigen, which is selectively present in male germ cells with maximal levels (dark-brown staining) at spermatogonia-spermatocyte stage,…
Model name Company Patient port size [mm] PET detector ring FDA cleared PET CT Diameter [mm] [year] ECAT Accel CTI (Siemens) 562 N/A 824 2000 Discovery LS GE Healthcare 600…
Fig. 1.1 [18F]FDG Although PET facilities are rapidly increasing worldwide, the only PET radiopharmaceutical currently available for diagnosis is [18F]FDG. In keeping with this notion, [18F]FDG is by far the…
Diagram 2.1 Epigenetic dysregulation of the metabolic signaling pathways that control cell growth, survival, and chemoresistance mechanisms in DLBCL. Our previous studies have shown that deregulated NF-kB, NFAT, and STAT3…
Fig. 9.1 Types of dedicated breast PET scanners. (a) Positron emission mammography (PEM). (b) Fully tomographic dedicated breast PET with dual-plate detector rotating around the breast. (c) Fully tomographic dedicated…
