PET tracer Pooled detection rate for PET/CT Correlation between detection rate and serum calcitonin values Prognostic value Tolerance Radiation dose Radionuclide production Comparative costs Comparative availability Theranostic value FDG 59…
and Philippe Barthélémy1, 3 (1) Université de Bordeaux, Bordeaux, F-33076, France (2) CNRS, INCIA, UMR 5287, F-33400 Talence, France (3) INSERM U1212, UMR CNRS 5320, Bordeaux, F-33076, France Philippe Barthélémy Email:…
Variable Typical carcinoid Atypical carcinoid Large cell NEC Small cell NEC Mitoses per 2 mm2 (10HPF) <2 2–10 ≥10 ≥10 Necrosis Absent Often punctate Often, large zones Frequent, large zones…
Subtype % of total cases MTC (%) Pheo (%) HPT (%) Associated diseases MEN2A 91 98 Classical 46 100 50 25 Hirschsprung’s disease 5 100 20 Hirschsprung’s disease Cutaneous lichen…
Single Photon Emission Computed Tomography (SPECT) Radionuclide T 1/2 (h) Decay mode (%) E γ (keV) (%) Production mode 99mTc 6.02 IT (100) γ 141 (91) 99Mo/99mTc generator 111In 67.9…
Fig. 1.1 Types of neuroendocrine neoplasms according to structure, system or organ of insurgence. LCNEC large cell neuroendocrine carcinoma, SCLC small cell lung carcinoma, GEP gastroenteropancreatic tract. World Health Organization…
Fig. 16.1 68Ga-DOTA-NOC PET/CT images of a patient with a large pNEN of the pancreatic head (a,b,c; SUVmax 40) presenting three additional focal lesions at liver level (a,d,e; SUVmax=7.4). Teaching…
Fig. 3.1 MEN1 gene and missense mutations. (a) Genomic structure of the MEN1 gene. The 10 exons of the gene are shown as boxes that are sized with the indicated…
Fig. 20.1 Distribution of neuroendocrine tumors Except for the undisputed role of surgery in the management of neuroendocrine tumors, the development and registration of the somatostatin analogs (congeners) octreotide and…
Fig. 2.1 Representation of all reported pheochromocytoma/paraganglioma susceptibility genes, specifying the year of publication, with special attention to the genes involved in the hereditary predisposition to the disease (opaque colored…
