Oncohema Key

Fig. 1 Histology of grade 1, well-differentiated, duodenal neuroendocrine tumor (gastrinoma) from a patient with MEN1-associated ZES. a Hematoxylin and eosin stain. b Immunohistochemistry for gastrin. c Chromogranin A. d…

Emil Zuckerkandl. (Circa 1890, author unknown, public domain) Emil Zuckerkandl was born on September 1, 1849, in Gyӧr, Hungary, and died on May 28, 1910, in Vienna. He was a…

Portrait of Dr. Arthur M. Shipley. (Reproduction by Mark Teske, professional photographer at University of Maryland School of Medicine) Introduction Dr. Arthur M. Shipley was a renowned American surgeon and…

Dr. William Mayo. (By permission of the Mayo Foundation for Medical Education and Research. All rights reserved) The story of the first operation for insulinoma is fascinating but tragic. After…

Fig. 1 A 31-year-old male noted to have a unilateral neck mass following an upper respiratory infection has a paraganglioma in the right carotid body ( white arrows). (Images courtesy…

John H. Sipple, MD in 1976, president of Couse Irving Memorial medical staff Introduction Multiple endocrine neoplasia type 2A (Sipple syndrome) was first described by John H. Sipple in 1961…

  Mean age of onset (years) Frequency (%) Central nervous system (CNS)   Retinal hemangioblastomas 18 70 Craniospinal hemangioblastomas 29 60–90 Endolymphatic sac tumors 22–32 11–16 Visceral    Pheochromocytomas 30 10–20…

Robert M. Zollinger. Photograph taken for cover of Modern Medicine, May 25, 1964 Surgeons and physicians will always associate Dr. Zollinger with gastrinoma , the “Zollinger–Ellison syndrome,” which he and…

Hormones Precursor/activator Products Amines Tryptophan Serotonin 5-Hydroxytryptophan 5-HIAA Histidine Histamine Peptides Kallikrein Bradykinin Kallidin Tachykinins Substance P Neurokinin A Neurokinin B Neuropeptide K Hemokinin-1 – Motilin ACTH Chromogranin A Prostaglandins…

Fig. 1 (a) Intraoperative photo of small bowel obstruction due to kinking caused by neuroendocrine tumor. (b) CT scan image demonstrating the same neuroendocrine tumor (indicated by arrow) Carcinoid Syndrome…