Oncofertility Options for Young Women With Breast Cancer
Abstract Breast cancer is the most common cancer diagnosed in women in the United States. Approximately 12% of breast cancers are diagnosed in women younger than 44 years of age….
Radiotherapy and Regional Nodes
Abstract The importance of regional lymph nodes in breast cancer and their appropriate treatment has undergone dramatic changes in a relatively short period. Although oncologists once considered them the gold…
Radiation Complications and Their Management
Abstract This chapter discusses the potential complications associated with the use of radiotherapy for breast cancer. These may occur in the weeks during or after radiation, such as fatigue or…
Surgical Management of Early Breast Cancer
Abstract The advent of screening mammography and its widespread application has resulted in more patients being diagnosed with small invasive breast cancers. Most of these early breast cancer patients can…
Adjuvant Endocrine Therapy
Abstract Endocrine therapy is a key component of the adjuvant treatment of early-stage breast cancer. In this chapter, we review the current approach to adjuvant endocrine therapy for early-stage invasive…
Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approach
Abstract This chapter describes the evolution of therapy for locally advanced breast cancer. Optimal management requires coordinated multidisciplinary care. Current treatment paradigms for LABC include use of neoadjuvant chemotherapy; resection,…
Adjuvant and Neoadjuvant Systemic Therapies for Early-Stage Breast Cancer
Abstract Background: While surgery is still the cornerstone treatment for early stage breast cancer, a deeper understanding in breast cancer biology has led to improvements in systemic therapies that improve…
Lymphedema in the Postmastectomy Patient: Pathophysiology, Prevention, and Management
Abstract Lymphedema is the most dreaded complication of breast cancer surgery. It may result in functional, esthetic, and psychological problems, thereby affecting the quality of life of the breast cancer…
Partial Breast Irradiation: Accelerated and Intraoperative
Abstract Partial breast irradiation encompasses a variety of techniques including accelerated partial breast irradiation (APBI) and intraoperative radiation therapy (IORT). APBI includes multicatheter brachytherapy, applicator based brachytherapy, and external-beam techniques….
Breast Conserving Therapy for Invasive Breast Cancers
Abstract The combination of breast conservation surgery (BCS) and whole breast radiation therapy (WBRT) is an effective alternative to mastectomy for the majority of women with early-stage invasive breast cancer,…
