Epithelioid Sarcoma
23117 Epithelioid Sarcoma Andrea P. Espejo-Freire and Jonathan C. Trent Epithelioid sarcoma (ES) is an aggressive malignant soft tissue sarcoma (STS) that mainly affects young adults. It is often multifocal…
Perivascular Epithelioid Cell Sarcoma
33726 Perivascular Epithelioid Cell Sarcoma Emily E. Jonczak Perivascular epithelioid cell neoplasms (PEComas) are a rare family of mesenchymal tumors, composed of histologically and immunohistochemically distinctive cells known as perivascular…
Chondrosarcoma
16112 Chondrosarcoma Jonathan C. Trent and Luyuan Li Chondrosarcomas constitute a heterogeneous group of malignant cartilaginous matrix-producing bone neoplasms with diverse morphologic features and clinical behavior. Following osteosarcoma, chondrosarcoma is…
Dedifferentiated Liposarcoma
1259 Dedifferentiated Liposarcoma William W. Tseng, Angelo Paolo Dei Tos, Roberta Giovanna Sanfilippo, Jennifer Wang, and Alessandro Gronchi Dedifferentiated (DD) liposarcoma is a high-grade, adipocytic malignancy and can be considered…
Alveolar Soft Part Sarcoma
20915 Alveolar Soft Part Sarcoma Emily E. Jonczak and Breelyn A. Wilky Alveolar soft part sarcoma (ASPS) is a rare, translocation-driven soft tissue sarcoma (STS) classically affecting adolescents and young…
Gastrointestinal Stromal Tumor
13710 Gastrointestinal Stromal Tumor César Serrano and Suzanne George Gastrointestinal stromal tumors (GISTs) span a wide clinical spectrum that ranges from lesions with essentially no metastatic potential to malignant and…
Surgical Oncology
132 Surgical Oncology Mark Fairweather and Chandrajit P. Raut Soft tissue sarcomas are composed of a heterogeneous group of tumors that demonstrate distinctive clinical behavior based on their inherent tumor…
Leiomyosarcoma
1178 Leiomyosarcoma Amanda Parkes and Neeta Somaiah Leiomyosarcoma (LMS) is a relatively common type of soft tissue sarcoma, commonly with an aggressive clinical course. The two broad categories of LMS…
Radiation Oncology
434 Radiation Oncology Jessica W. Lee and David G. Kirsch Radiation therapy (RT) uses ionizing radiation (IR), which damages DNA to exert the end effect of cell death. IR is…
Medical Oncology
31 Medical Oncology Ravin Ratan and Shreyaskumar R. Patel Localized approaches such as surgery and radiation therapy are the mainstay for localized, resectable, low-risk sarcoma patients. However, a significant portion…
