of DCIS and Progression to Invasive Disease
Fig. 1 The stages of breast cancer. Within the normal mammary duct and TDLU, an inner layer of luminal epithelial cells and a basal layer of myoepithelial cells are surrounded by…
Clinical Role of Genetic Profiling in Breast Cancer
Fig. 1 a The final gene list (16 cancer-related and five reference genes) and summary score (recurrence score) algorithm for this assay were developed by analyzing the results of three independent…
Amplification of ErbB-2: From Gene to Therapy
Fig. 1 ErbB signaling pathway 4 ErbB-2 Gene Amplification and Overexpression in Breast Cancer The ErbB-2 proto-oncogene gene is amplified and is considered the main mechanism of ErbB-2 protein overexpression in…
Therapies in Breast Cancer
Arora H, Jensen M, Yuan Y, Wo A, Vogt S, Paunesku T et al (2012) Nanocarriers enhance doxorubicin uptake in drug-resistant ovarian cancer cells. Cancer Res 72(3):769–778PubMedCentralPubMed Astsaturov I, Cohen…
Syndromes and Radiotherapy in Breast Cancer
© Springer-Verlag Berlin Heidelberg 2015Jonathan Strauss, William Small and Gayle E. Woloschak (eds.)Breast Cancer Biology for the Radiation OncologistMedical Radiology10.1007/174_2014_1046 Genetic Syndromes and Radiotherapy in Breast Cancer Camille Green1 , Atif J. Khan1 and Bruce G. Haffty1 (1) Department of Radiation…
Basis of Normal Tissue Radiosensitivity and Late Toxicity in Breast Cancer
Cancer Patients studied Assay Association References Breast cancer Breast/various 23 (16 breast) PTT No Appleby et al. (1997) Breast 15 PTT No Ramsay et al. (1998) Breast/various 5 PTT No…
Subtypes of Breast Cancer
© Springer-Verlag Berlin Heidelberg 2015Jonathan Strauss, William Small and Gayle E. Woloschak (eds.)Breast Cancer Biology for the Radiation OncologistMedical Radiology10.1007/174_2014_1043 Biological Subtypes of Breast Cancer Sara E. Barnato1 and William J. Gradishar1 (1) Northwestern University, 676 N. St. Clair,…
Stem Cells and Radiotherapy
Fig. 1 a The ROS and nuclear DNA damages induced by radiation can activate NFκB that in turn enters into the nucleus and binds to the promoter of HER2 gene causing…
