Classic Epidemiology of Lung Cancer
Summary of Key Points • Lung cancer incidence and mortality has declined among men in many countries, following a decline in the prevalence and level of smoking. Among women, lung…
ONCOLOGY
Chemoprevention of Lung Cancer and Management of Early Lung Cancer
Summary of Key Points • Most chemoprevention research is focused on natural products and is not amenable to traditional pharmaceutical development. • Robust research and development for lung cancer chemoprevention…
Gender-Related Differences in Lung Cancer
Summary of Key Points • Epidemiology of lung cancer is still changing: in the last 10 years lung cancer became the first cause of cancer-related deaths in both men and…
Tobacco Control and Primary Prevention
Summary of Key Points • Smoking is the predominant risk factor for development of lung cancer. As tobacco is introduced to societies, common patterns emerge. Typically, it is first used…
Screening for Lung Cancer
Summary of Key Points • The National Lung Screening Trial has definitively shown a reduction in lung cancer mortality in a research setting but effective implementation of a lung cancer…
Genetic Susceptibility to Lung Cancer
Summary of Key Points • While 85% to 90% of lung cancer is attributable to cigarette smoking, substantial evidence exists to support genetic susceptibility to this disease. • A family…
Lung Cancer in Never-Smokers: A Different Disease
Summary of Key Points • The known or suspected etiologic factors for lung cancer arising in never-smokers are weak carcinogens or rare factors, which cannot explain the relatively high frequency…
Assessing and Treating Tobacco Use in Lung Cancer Care
Summary of Key Points • Addressing tobacco dependence in patients with cancer increases the quality of care by reducing their risk for treatment complications, improving their prognosis, and reducing the…
Treatment of Screen-Detected Breast Cancer: Can We Avoid or Minimize Overtreatment?
Chapter Outline Plain Language Summary 375 Introduction 376 Reducing Cancer Diagnoses 379 Changing Terminology 380 Less Surgery for In Situ Breast Cancer 382 Reduced Treatment for DCIS 384 Limiting Radiotherapy…
Informed and Shared Decision Making in Breast Screening
Chapter Outline Plain Language Summary 403 Introduction 404 Public Perceptions of Screening 404 The Conventional Approach to Information Provision 406 The Need for Shared/Informed Decision Making in Screening 406 What…
