Summary of Key Points • Maintenance therapy offers the possibility of continued active treatment to delay disease progression and symptom deterioration and, more importantly, improved overall survival of patients with…

Summary of Key Points • There are a growing proportion of patients who are candidates for second-line therapy and beyond. • Treatment choices are dictated by tumor histology, molecular phenotype…

Summary of Key Points • The acute and late toxicity of radiotherapy (RT) for lung cancer usually involves the lungs, esophagus, and heart. Lung • Post-RT, there are multiple biochemical…

Summary of Key Points • The determination of tumor histology in nonsmall cell lung cancer (NSCLC) has become essential in treatment decision-making due to differential efficacy and toxicities seen with…

Summary of Key Points • Palliative radiotherapy is an effective and well tolerated treatment for palliation of thoracic and other symptoms in patients with lung cancer (both nonsmall cell lung…

Summary of Key Points • Concerning radiotherapy, higher physical or biologic dose (altered fractionation) is associated with better local control and, in some trials, with better survival. Current evidence favors…

Summary of Key Points • Since the initial identification of radiofrequency ablation (RFA) as the prototypical thermal ablation technique, it has been joined by microwave ablation, cryoablation, and, more recently,…

Summary of Key Points • Stereotactic ablative radiotherapy (SABR) is recommended in treatment guidelines as the nonoperative therapy of choice for early-stage nonsmall cell lung cancer (NSCLC). • SABR can…