Diagnostic Tools in the Evaluation and Management of Penile Cancer
Fig. 2.1 Magnetic resonance imaging of a penile carcinoma of the glans with the proximal extent of tumor seen on the penile shaft There is recent evidence to suggest that…
ONCOLOGY
New Systemic Approaches and Clinical Trials in Penile Cancer
General class Mechanism Examples Conventional cytotoxic drugs Platinating DNA damaging agents Cisplatin Cyclophosphamide Bleomycin Microtubule agents Vinblastine Paclitaxel Antimetabolites Gemcitabine 5-fluorouracil Targeted drugs Cell surface and intracytoplasmic tyrosine kinase enzymatic…
Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions
Fig. 1.1 Schematic diagram illustrating molecular pathways implicated in HPV- and non-HPV-associated penile cancer. Reprinted with permission from [57] In these situations, the E7 protein instead complexes with pRb which…
Dynamic Sentinel Node Biopsy and FDG-PET/CT for Lymph Node Staging in Penile Cancer
Fig. 4.1 Lymphatic drainage in penile cancer. Anterior planar lymphoscintigraphy (a) shows drainage from the central injection site to both groins. On SPECT/CT (volume rendered, b and transversal slices c,…
Head and Neck Cancer Biomarkers in Circulation
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Molecular pathology of head and neck cancer (HNC) Circulating cell-free…
Renal Cell Carcinoma Biomarkers in Circulation
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Molecular pathology of renal cell carcinoma (RCC) Circulating cell-free nucleic…
Brain Tumor Biomarkers in Circulation
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Molecular pathology of brain tumors. Circulating glioblastoma (GBM) epigenetic biomarkers….
Pancreatic Cancer Biomarkers in Circulation
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Challenges with pancreatic cancer (PanCa) screening Screening for PanCa Molecular…
Endometriosis Biomarkers in Body Fluids
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Molecular pathology of endometriosis. Circulating endometriosis miRNA biomarkers. Circulating endometriosis…
Ovarian Cancer Biomarkers in Circulation
(1) Medical Sciences Division Northern Ontario School of Medicine West Campus, Lakehead University, Thunder Bay, Ontario, Canada Key Topics Molecular pathology of ovarian cancer (OvCa). Circulating OvCa biomarkers. Circulating…
