Anaplastic Large Cell Lymphoma
Fig. 6.1 (a and b) ALCL, ALK- with large tumor cells containing pleomorphic nuclei 6.3 Immunophenotype The tumor cells of ALCL, ALK-positive and ALK-negative, universally express CD30 and a majority…
ONCOLOGY
of T-Cell Lymphomas: Diagnosis and Biomarker Discovery
Mature leukemias • T-cell prolymphocytic leukemia • T-cell large granular lymphocytic leukemia • Chronic lymphoproliferative disorders of NK-cells • Aggressive NK-cell leukemia • Adult T-cell leukemia/lymphoma • Sezary syndrome Mature…
Expression Profiling in Non-Hodgkin Lymphomas
Fig. 1 A Performance of the Lymph2Cx assay using an abbreviated gene set (20 genes) compared to the “gold standard method” of previously reported GEP as well as three IHC-based algorithms…
of Diffuse Large B-Cell Lymphoma (DLBCL)
Prognostic group # risk factorsa Low risk 0, 1 Low intermediate 2 High intermediate 3 High 4, 5 aelevated LDH, advanced stage (Ann Arbor III/IV), age > 60, ≥ 2 extralymphatic sites of involvement…
Therapeutic Strategies and New Treatment Paradigms for Follicular Lymphoma
Fig. 1 a Kaplan–Meier curve showing progressive improvement in the overall survival of FL patients over time. b Patients diagnosed and treated in post-rituximab era-2 (light color) had a statistically significant…
and Etiology of Non-Hodgkin Lymphoma
Fig. 1 Incidence Rates of NHL subtypes in the USA, 2000–2011, Surveillance, Epidemiology, and End-Results Program (Surveillance Research Program, National Cancer Institute SEER*Stat software (www.seer.cancer.gov/seerstat), Version 8.1.5. Surveillance, Epidemiology, and End…
Prognosis, and Therapy of Waldenström Macroglobulinemia
IgM monoclonal gammopathy of any concentration Bone marrow infiltration by small lymphocytes showing plasmacytic differentiation Intertrabecular pattern of bone marrow infiltration Surface IgM+, CD19+, CD20+, CD22+, CD25+. CD27+, FMC7+, CD5±,…
of Non-Hodgkin Lymphomas: Diagnosis and Response-Adapted Strategies
1 No uptake 2 Uptake ≤ mediastinum 3 Uptake > mediastinum but ≤ liver 4 Uptake moderately higher than liver 5 Uptake markedly higher than liver and/or new lesions X New areas of uptake unlikely to…
Lymphoproliferative Disorders
Fig. 1 The histopathology of PTLD. a Infectious mononucleosis-like “early” PTLD lesion. b Monomorphic PTLD, Burkitt lymphoma type. c Polymorphic PTLD. d Positive EBV in situ hybridization stain in a PTLD…
of the Marginal Zone Lymphomas
Site Procedure Gastric MALT lymphoma Stomach • Endoscopic ultrasound • H. pylori status (by IHC)a • FISH or molecular assay for the t(11;18) translocation Non-gastric MALT lymphoma Breast • Mammography…
