Fig. 1 Range of surgical approaches to recurrent oropharyngeal squamous cell carcinoma (OPSCC). TLM Transoral laser microsurgery. TORS Transoral robotic surgery Patient selection is critical to the successful application of surgery…
Primary tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ T1 Tumor = 2 cm in greatest dimension T2 Tumor > 2 cm but not more than…
Fig. 1 VU University Medical Centre HPV test algorithm 3.2 The Johns Hopkins Medical Institutions HPV Test Algorithm This algorithm (Fig. 2) was developed by The Johns Hopkins Medical Institutions, USA (Singhi…
Fig. 1 Treatment options of oropharyngeal cancer An important concept in selecting a surgical approach is to develop a clear “concept of operation”. This means that the surgeon selects the most…
Fig. 1 Classification of risk groups for survival of OPSCC using RPA analysis of 2 RTOG trials by Ang et al. (2010) In 2013, Rietbergen et al. conducted a study, based…
First author Year Anatomical site HPV- HPV+ Differently expressed genes (probes) Analyzed genes (probes) Oropharynx Oral cavity Tonsils Base of tongue/tongue Larynx Hypopharynx Keck 2014 X X X 75 55…
Cervarix Gardasil Gardasil 9 HPV coverage 16, 18 6, 11, 16, 18 6, 11, 16, 18, 31, 33, 45, 52, 58 Manufacturer GlaxoSmithKline Merck Merck Producing cells Trichoplusia ni…
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_20 Update on De-intensification and Intensification Studies in HPV Hisham Mehanna1, 2 (1)…
Fig. 1 Phylogenetic tree of the HPV16 variants identified by Yamada et al. (1995) in the United States within a sample of 30 HPV16 isolates based on parsimony analysis. Combined sequences…
© Springer International Publishing Switzerland 2017Wojciech Golusiński, C. René Leemans and Andreas Dietz (eds.)HPV Infection in Head and Neck CancerRecent Results in Cancer Research20610.1007/978-3-319-43580-0_19 Cancer Immunology and HPV Barbara Wollenberg1 (1) Department of Otorhinolaryngology, University of…
