ONCOLOGY

Radiation Therapy for Soft Tissue Sarcoma

Sep 27, 2017 by in ONCOLOGY Comments Off on Radiation Therapy for Soft Tissue Sarcoma

Soft tissue sarcomas are rare mesenchymal cancers that pose a treatment challenge. Although small superficial soft tissue sarcomas can be managed by surgery alone, adjuvant radiotherapy in addition to limb-sparing…

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Dermatofibrosarcoma Protuberans

Sep 27, 2017 by in ONCOLOGY Comments Off on Dermatofibrosarcoma Protuberans

Dermatofibrosarcoma protuberans (DFSP) is a rare dermal soft tissue sarcoma characterized by a typically indolent clinical course. The greatest clinical challenge in management of DFSP is achieving local control. There…

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Malignant Peripheral Nerve Sheath Tumor

Sep 27, 2017 by in ONCOLOGY Comments Off on Malignant Peripheral Nerve Sheath Tumor

Malignant peripheral nerve sheath tumor (MPNST) is the sixth most common type of soft tissue sarcoma. Most MPNSTs arise in association with a peripheral nerve or preexisting neurofibroma. Neurofibromatosis type…

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Myxofibrosarcoma

Sep 27, 2017 by in ONCOLOGY Comments Off on Myxofibrosarcoma

Myxofibrosarcoma is a unique subtype of soft tissue sarcoma with a locally infiltrative behavior. High-quality MRI imaging is critical for preoperative planning. Wide surgical resection with a 2 cm soft…

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Modern Neuroimaging of Pediatric Brain Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Modern Neuroimaging of Pediatric Brain Tumors

Fig. 13.1 High-grade glioma with both improved spectra and anatomic imaging after receiving radiation therapy. (a1–a3) Pretreatment 3D chemical shift imaging (CSI) transposed on T1-weighted gadolinium-enhanced axial image. Spectrum voxel…

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Embryonal Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Embryonal Tumors

Fig. 5.1 Hematoxylin and eosin micrograph of classic medulloblastoma. There are dense sheets of small round blue cells with scant cytoplasm Fig. 5.2 Hematoxylin and eosin micrograph of Homer-Wright rosettes…

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Brainstem Gliomas

Sep 26, 2017 by in ONCOLOGY Comments Off on Brainstem Gliomas

Tumor type Approximate frequency (%) Clinical characteristics Imaging characteristics Predominant pathology Diffuse intrinsic 75–85 Multiple bilateral CN deficits LTS Ataxia Short clinical history Diffuse pontine enlargement T1 hypointensity T2 variable…

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Neurocutaneous Syndromes and Associated CNS Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Neurocutaneous Syndromes and Associated CNS Tumors

Major features Minor features Café au lait spots and skin freckling Macrocephaly Peripheral neurofibromas Short stature as growth hormone deficiency found in NF1 patients that do not even have hypothalamic…

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Advances in Radiation Therapy

Sep 26, 2017 by in ONCOLOGY Comments Off on Advances in Radiation Therapy

Fig. 16.1 A 21-year-old female with history of grade 3 pineal parenchymal tumor of intermediate differentiation (PPTID) status post gross total resection (GTR) receiving adjuvant whole ventricular radiation therapy. Top…

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Current Surgical Management

Sep 26, 2017 by in ONCOLOGY Comments Off on Current Surgical Management

Fig. 14.1 Intraoperative ultrasound images of a 4-year-old boy with a low-grade glioma of the left frontal lobe. Preresection (a) and postresection (b) coronal plane images demonstrate the distinct echogenicity…

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