Ophthalmologic Disease
Chapter 66 Ophthalmologic Disease Douglas A. Jabs, MD, MBA, Jennifer E. Thorne, MD, PhD Ocular manifestations are common in patients with AIDS, and in the era before highly active antiretroviral…
INFECTIOUS DISEASE
AIDS Psychiatry
Chapter 63 AIDS Psychiatry Alex Thompson, MD, MBA, Benjamin C. Silverman, BA, Andrew Angelino, MD, Glenn J. Treisman, MD, PhD INTRODUCTION HIV infection is spread through intimate contact, which involves…
Tipranavir
Chapter 25 Tipranavir Véronique Joly, MD, Patrick Yeni, MD INTRODUCTION The availability of potent antiretroviral drugs, including protease inhibitors (PI), and their use in combination regimens–highly active antiretroviral therapy (HAART)–has…
HIV-Related Renal Disease
Chapter 70 HIV-Related Renal Disease Jonathan A. Winston, MD, Paul E. Klotman, MD Diseases of the kidney are generally classified into one of two broad clinical syndromes, acute renal failure…
Bone Disorders
Chapter 75 Bone Disorders Val Amorosa, MD, Pablo Tebas, MD OSTEOPOROSIS Introduction Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced…
Histoplasmosis
Chapter 44 Histoplasmosis Lawrence J. Wheat, MD INTRODUCTION Histoplasmosis is a serious opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS) in endemic regions of America, Africa, and Asia, although…
Inhibiting the Entry of R5 and X4 HIV-1 Phenotypic Variants
Chapter 24 Inhibiting the Entry of R5 and X4 HIV-1 Phenotypic Variants Shawn E. Kuhmann, PhD, Roy M. Gulick, MD, MPH, John P. Moore, PhD Compounds that prevent HIV-1 from…
Lactic Acidosis and Other Mitochondrial Disorders Associated with HIV Therapy
Chapter 74 Lactic Acidosis and Other Mitochondrial Disorders Associated with HIV Therapy David Nolan, MD, Simon Mallal, MD INTRODUCTION Nucleoside analog reverse transcriptase inhibitors (NRTI) were the first class of…
Candidiasis
Chapter 46 Candidiasis Carl J. Fichtenbaum, MD, Peter G. Pappas, MD INTRODUCTION Oropharyngeal candidiasis (OPC) was among the initial manifestations recognized in association with human immunodeficiency virus (HIV) infection,1,2 affecting…
Sexually Transmitted Infections
Chapter 58 Sexually Transmitted Infections Lara B. Strick, MD MSc, Christina M. Marra, MD, Connie L. Celum, MD, MPH INTRODUCTION The importance of the bidirectional relationship between human immunodeficiency virus…
