Modifications to Blood Components
Blood component modifications can be performed by the hospital blood bank for select clinical indications. In general, modification of blood components increases costs and may delay availability of the blood…
HEMATOLOGY
Red Blood Cell Antibodies in Hematology/Oncology Patients
Red blood cell (RBC) transfusion is a cornerstone of the management of patients with hematology/oncology disorders. However, a potentially deleterious consequence of transfusion is the development of alloantibodies against blood…
Pathogen Inactivation Technologies
Pathogen inactivation technologies represent a shift in blood safety from a reactive approach to a proactive protective strategy. Commercially available technologies demonstrate effective killing of most viruses, bacteria, and parasites…
Transfusion Reactions
Transfusion reactions are common occurrences, and clinicians who order or transfuse blood components need to be able to recognize adverse sequelae of transfusion. The differential diagnosis of any untoward clinical…
Management of Patients with Sickle Cell Disease Using Transfusion Therapy
Red blood cell (RBC) transfusion therapy is a key component of comprehensive management of patients with sickle cell disease (SCD) and has increased over time as a means of primary…
Autologous Stem Cell Mobilization and Collection
Peripheral blood stem cell collection is an effective approach to obtain a hematopoietic graft for stem cell transplantation. Developing hematopoietic stem/progenitor cell (HSPC) mobilization methods and collection algorithms have improved…
Assessing the Rationale and Effectiveness of Frozen Plasma Transfusions
Frozen plasma is a commonly used blood product. The primary indications for frozen plasma are the treatment and prevention of bleeding in patients with prolonged coagulation tests. However, there is…
Platelet Transfusions in Patients with Hypoproliferative Thrombocytopenia
Patients with hematologic malignancies frequently become thrombocytopenic as a result of their underlying malignancy or treatments, including cytotoxic chemotherapy and hematopoietic stem cell transplantation and are at increased risk of…
Transfusion Medicine
Jeanne E. Hendrickson, MD, Editor Christopher A. Tormey, MD, Editor Transfusion is essential for the care of a great number of individuals with Hematologic and Oncologic disorders; pediatric and adult…
Red Blood Cell Transfusion Strategies in Adult and Pediatric Patients with Malignancy
Anemia in patients with malignancy is common as a consequence of their disease and treatment. Substantial progress has been made in the management of anemia with red blood cell transfusion…
