Fig. 6.1 Schematic representation of development of primordial follicle to pre-ovulatory Graafian follicle. BL Basement laminae, O Oocyte, GC Granulosa cell, ZP Zona pellucida, TC Theca cell, FF Follicular fluid, BV…
© Springer International Publishing AG 2017Ri-Cheng Chian, Geeta Nargund and Jack Y. J. Huang (eds.)Development of In Vitro Maturation for Human Oocytes10.1007/978-3-319-53454-1_10 10. Risk Factors and Preventive Measures of Ovarian Hyperstimulation Syndrome Byung-Chul Jee1 (1) Department of…
Fig. 7.1 The overall picture of ovarian stimulation protocol: two most commons Conclusion Controlled ovarian stimulation is the fundamental program in IVF treatment. Fine-tuning of ovarian stimulation for the purpose of…
Fig. 3.1 The regulation of oocyte meiotic prophase arrest and resumption in mammals. NPPC produced by mural granulosa cells stimulates the generation of cGMP by NPR2 of cumulus cells. The cGMP…
Study Year Method Patients (n) Age (years) Cycles (n) FR (%) PR/ET (%) Kedem et al. [8] 2014 Modified NC-IVF/ICSI in POR 111 39 111 0.67 0.9 Von Wolff et…
Fig. 7.1 Locations of missense PAX8 mutations (secondary structure). Amino acid sequences of human PAX genes (PAX1 to PAX9) are shown. The sequences correspond to the paired domain, which consists…
Main causes Inheritable defects CPHDs Pituitary transcription factor defects LEPR or PROKR2 mutations Isolated CH TSHβ, TRHR or IGSF1 mutations Invasive or compressive lesions Craniopharyngiomas Pituitary macroadenomas Meningiomas or gliomas…
Fig. 19.1 Generation of functional thyroid follicles from pluripotent stem cells. (a) Schematic diagram of the thyroid follicle differentiation protocol from ESCs. (b) Expression of endogenous Nkx2-1 and Pax8, Foxe1,…
Thyroid-related causes Systemic causes Hashimoto’s thyroiditis Diabetes mellitus Iodine deficiency Celiac disease Overtreatment of Graves’ disease Chronic renal failure Transient neonatal hyperthyrotropinemia Syndromes (Turner, Down …) Variations in genes of…
Fig. 1.1 Early stage of mammalian development. Panel a: Schematic cross-section of a mammalian embryo after gastrulation. The position of three germ layers, ectoderm (brown), mesoderm (orange), and endoderm (green)…
