Keypoints Type 1 diabetes mellitus (T1DM) develops in genetically susceptible individuals after a preclinical phase of variable length usually with immune-mediated destruction of pancreatic β-cells, and requires lifelong treatment with…
Keypoints Diabetic ketoacidosis Lack of insulin is the culprit in diabetic ketoacidosis. The most common precipitating cause is infection. The classic signs include polyuria and polydipsia, rapid weight loss, weakness,…
Keypoints Insulin signaling is accurately viewed as involving a matrix of interacting pathways, allowing for extensive modulation and divergence in signal transduction, rather than a linear cascade of sequential reactions….
Keypoints People with diabetes should be seen as individuals with a condition that has medical, personal and social consequences, instead of being passive recipients of health care. The optimal management…
Keypoints Diabetes education is an important cornerstone of diabetes care, and supports the philosophy of the chronic disease model. Diabetes education improves clinical outcomes, and requires periodic follow-up. Time spent…
