Exenatide clinical efficacy The Phase 3 clinical efficacy studies that have been conducted with exenatide are listed in Table 4.1. Three 30-week, placebo-controlled studies evaluated exenatide (5 µj.g or 10…

In a 52-week active-comparator study, patients not achieving adequate glycaemic control on a metformin dose of at least 1500 mg/day were randomized to sitagliptin 100 mg once daily or glipizide,…

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Figure 6.2 Adjusted mean (95% CI) percent change from baseline in body weight after 12 weeks of dapagliflozin treatment. Reproduced from List et al. (2009) with permission from the American…