Most patients with corticotropin (ACTH)-dependent Cushing syndrome (CS) will have an ACTH-secreting pituitary tumor. However, approximately 10%–15% of patients with ACTH-dependent CS have an ectopic source of ACTH secretion (see…
Corticotropin (ACTH)-dependent hypercortisolism is commonly due to an ACTH-secreting pituitary adenoma (80%–90%). Most patients with ACTH-dependent hypercortisolism are women with slowly progressive mild to moderate Cushing syndrome (CS) who will…
There is no cure for metastatic paraganglioma or pheochromocytoma (PPGL). All treatment options are associated with risks and morbidity—many times the side effects of treatment exceed tumor-related morbidity. The first…
A higher incidence of paraganglioma or pheochromocytoma (PPGL) has been reported in people living at high altitudes, indicating that environmental hypoxia could be a risk factor for development of PPGL….
There is no cure for metastatic pheochromocytoma or metastatic paraganglioma (PPGL). The first step in the management of metastatic PPGL is to assess the rate of tumor progression and, once…
There is no cure for metastatic paraganglioma (PGL). The first step in the management ofmetastatic PGL is to assess the rate of tumorprogression and, once determined, provide a proportionate treatment….
Carney triad (described in 1977) is a rare, nonfamilial, multitumoral syndrome, with three tumors in the initial description: gastrointestinal stromal tumor (GIST), pulmonary chondroma, and extraadrenal paraganglioma (PGL). , Subsequently,…
There is no cure for metastatic pheochromocytoma or paraganglioma (PPGL). The first step in the management of metastatic PPGL is to assess the rate of tumor progression and, once determined,…
There is no cure for metastatic pheochromocytoma or metastatic paraganglioma (PPGL). The first step in the management of metastatic PPGL is to assess the rate of tumor progression and, once…
Multiple endocrine neoplasia type 2B (MEN2B) is an autosomal dominant disorder with age-related penetrance, and it represents approximately 5% of all MEN2 cases. MEN2B is characterized by medullary thyroid carcinoma…
