Summary of Key Points • The acute and late toxicity of radiotherapy (RT) for lung cancer usually involves the lungs, esophagus, and heart. Lung • Post-RT, there are multiple biochemical…
Summary of Key Points • The determination of tumor histology in nonsmall cell lung cancer (NSCLC) has become essential in treatment decision-making due to differential efficacy and toxicities seen with…
Summary of Key Points • Radiation-induced brachial plexopathy (RIBP) occurs with treatment of apical tumors and is frequently complicated by tumor-related brachial plexopathy (TRBP). Stereotactic ablative radiotherapy (SABR) of apical…
Summary of Key Points • Palliative radiotherapy is an effective and well tolerated treatment for palliation of thoracic and other symptoms in patients with lung cancer (both nonsmall cell lung…
Summary of Key Points • Concerning radiotherapy, higher physical or biologic dose (altered fractionation) is associated with better local control and, in some trials, with better survival. Current evidence favors…
Summary of Key Points • In patients with clinically nonmetastatic small cell lung cancer (SCLC), positron emission tomography–computed tomography (PET–CT) as well as brain imaging is suggested to classify tumor…
Summary of Key Points • Since the initial identification of radiofrequency ablation (RFA) as the prototypical thermal ablation technique, it has been joined by microwave ablation, cryoablation, and, more recently,…
Summary of Key Points • Stereotactic ablative radiotherapy (SABR) is recommended in treatment guidelines as the nonoperative therapy of choice for early-stage nonsmall cell lung cancer (NSCLC). • SABR can…
Summary of Key Points • Patient selection is crucial to ensure treatment selection and optimal outcome. • The performance status, described by, for example, the Karnofsky or the Eastern Cooperative…
Summary of Key Points • The hallmarks of radiobiology are the “4 Rs”: r epair, r eassortment, r eoxygenation, r epopulation. • Radiation exerts its biologic effects by causing damage…
