Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia
## There are six subtypes of primary aldosteronism (PA). The most common subtype of PA is bilateral idiopathic adrenal hyperplasia (IHA) (≈60% of patients) (see Case 8). The second most…
Primary Aldosteronism With Bilateral Adrenal Nodules on Computed Tomography
## The differential diagnosis in a patient with primary aldosteronism (PA) when bilateral adrenocortical nodules are found on adrenal computed tomography (CT) scan includes bilateral idiopathic nodular hyperplasia, bilateral aldosterone-producing…
Primary Aldosteronism With Unilateral Adrenal Nodule on Computed Tomography
## Cross-sectional computed imaging lacks the necessary accuracy to determine if a patient has unilateral adrenal versus bilateral adrenal disease as the cause of primary aldosteronism (PA). If abdominal computed…
Primary Aldosteronism: When Adrenal Venous Sampling Is Not Needed Before Unilateral Adrenalectomy
## There is a small subset of patients (≈5%) with primary aldosteronism (PA) in whom surgical management can proceed without the need for adrenal venous sampling (AVS). This subset includes…
54-Year-Old Woman With an Incidentally Discovered Adrenal Mass and Abnormal Dexamethasone Suppression Test: Role of Adrenalectomy
## Mild autonomous cortisol secretion (MACS) is defined as an abnormal cortisol concentration following dexamethasone suppression test (post-DST cortisol >1.8 mcg/dL) and is detected in up to 50% of patients…
Lipid-Poor Adrenal Masses: The Case for Aggressive Management
## Lipid-poor adrenal masses are the landmines of adrenal disorders. Although lipid-poor adrenal masses may be benign nonfunctional cortical adenomas, it can be difficult to make the distinction from more…
Nonfunctioning Lipid-Rich Adrenocortical Adenoma: Role of Follow-Up
## Any adrenal mass needs evaluation for adrenal hormonal excess and malignancy. , Imaging characteristics can be helpful to exclude malignancy. Workup for adrenal hormone excess includes assessment for cortisol,…
Incidentally Discovered Adrenal Mass in a Patient With a History of Extraadrenal Malignancy: The Role of Adrenal Biopsy
## Adrenal metastasis should be suspected in any patient with history of extraadrenal malignancy presenting with an indeterminate adrenal mass. The most common extraadrenal malignancies that metastasize to adrenal gland…
Adrenal Mass in a Patient With a History of Extraadrenal Malignancy: The Role of Imaging
## Adrenal metastasis should be suspected in any patient with a history of extraadrenal malignancy presenting with an indeterminate adrenal mass. Full hormonal workup and assessment of imaging characteristics are…
45-Year-Old Woman With an Incidentally Discovered Large Adrenal Mass
## Adrenal tumors >4 cm in diameter represent 17% of adrenal tumors seen in the tertiary endocrine center. The proportion of malignant adrenal tumors and pheochromocytomas is high in large…
