ACTIONS OF THE MINERALOCORTICOIDS Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ In order of decreasing potency, the mineralocorticoids include aldosterone, 11-deoxycorticosterone, 18-oxocortisol, corticosterone, and cortisol. As a class of hormones,…
ACTIONS OF THE GLUCOCORTICOIDS Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ Glucocorticoids are essential for survival. The term glucocorticoid refers to the glucose-regulating properties of these hormones. However, the glucocorticoids…
GENERAL MECHANISMS OF ACTION Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ The steroid hormones, vitamin D, retinoic acid, and the thyroid hormones all share a similar mechanism of action.1,2 These…
CORTICOSTEROID ACTION Perrin C. White GENERAL MECHANISMS OF ACTION Related posts: REGULATION OF THE GROWTH HORMONE RECEPTOR AND BINDING PROTEIN GONADOTROPE ADENOMAS OF THE PITUITARY PROLACTIN HYPERSECRETION DEFINITIONS THYROID-HORMONE RECEPTOR…
METABOLISM Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ The liver and the kidney are the principal organs involved in clearing the steroid hormones from the circulation. Although…
ALTERATIONS IN BINDING PROTEINS Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ Generally, it is the total level of a hormone that is measured. Many factors can alter…
DISTRIBUTION IN THE CIRCULATION Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ Substantial variability exists in the production rate of the various steroids by males and females (see…
REGULATION OF ADRENAL CORTICOSTEROID PRODUCTION Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ CORTISOL SECRETION ADRENOCORTICOTROPIC HORMONE ACTH is a 39-amino-acid peptide that is produced in the anterior…
BIOSYNTHESIS Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ IMPORTATION INTO MITOCHONDRIA The rate-limiting step in steroid biosynthesis is importation of cholesterol from cellular stores to the matrix…
