PHEOCHROMOCYTOMA AND OTHER DISEASES OF THE SYMPATHETIC NERVOUS SYSTEM
PHEOCHROMOCYTOMA AND OTHER DISEASES OF THE SYMPATHETIC NERVOUS SYSTEM Harry R. Keiser PHEOCHROMOCYTOMA
PATTERNS OF CATECHOLAMINERGIC ACTIVATION
PATTERNS OF CATECHOLAMINERGIC ACTIVATION Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ Sympathoneural and adrenomedullary activation in response to physiologic or pharmacologic manipulations…
DIRECT MEASUREMENT OF SYMPATHETIC NEURAL ACTIVITY
DIRECT MEASUREMENT OF SYMPATHETIC NEURAL ACTIVITY Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ Microneurography can measure sympathetic neural activity from the rate…
CIRCULATING CATECHOLAMINES AND ACTIVITIES OF THE SYMPATHONEURAL AND ADRENOMEDULLARY SYSTEMS
CIRCULATING CATECHOLAMINES AND ACTIVITIES OF THE SYMPATHONEURAL AND ADRENOMEDULLARY SYSTEMS Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ Much of the catecholamine content…
EFFECTS OF CATECHOLAMINES
EFFECTS OF CATECHOLAMINES Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ CIRCULATION Cardiovascular function, both at rest and during stress, unquestionably depends on…
ADRENERGIC RECEPTORS
ADRENERGIC RECEPTORS Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ Specific receptors for catecholamines exist in several tissues, including muscle (skeletal, myocardial, vascular,…
PRESYNAPTIC MODULATION
PRESYNAPTIC MODULATION Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ NE can regulate its own release, by stimulating presynaptic, inhibitory α2-adrenergic receptors.18,19 Other…
CATECHOLAMINE REMOVAL
CATECHOLAMINE REMOVAL Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ The most prominent removal mechanism for released NE is reuptake into the presynaptic…
CATECHOLAMINE RELEASE
CATECHOLAMINE RELEASE Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ ACh depolarizes chromaffin cells by increasing membrane permeability to sodium. Transmembrane influx of…
CATECHOLAMINE SYNTHESIS
CATECHOLAMINE SYNTHESIS Part of “CHAPTER 85 – PHYSIOLOGY OF THE ADRENAL MEDULLA AND THE SYMPATHETIC NERVOUS SYSTEM“ The catecholamines contain a catechol (3,4-dihydroxyphenyl) nucleus (Fig. 85-2). Intracellular events in NE…
