ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD
ADRENOCORTICAL DISORDERS IN INFANCY AND CHILDHOOD Robert L. Rosenfield Ke-Nan Qin GENERAL PRINCIPLES ADRENOCORTICAL INSUFFICIENCY
ENDOCRINE ASPECTS OF HYPERTENSION
ENDOCRINE ASPECTS OF HYPERTENSION Dalila B. Corry Michael L. Tuck SPECTRUM OF HYPERTENSION Hypertension is an extremely common disorder, affecting 15% to 20% of the population. More than 95% of…
MINERALOCORTICOID RESISTANCE
MINERALOCORTICOID RESISTANCE Part of “CHAPTER 81 – HYPOALDOSTERONISM“ Mineralocorticoid resistance implies a lack of response to aldosterone despite its presence. Aldosterone binds to intracellular mineralocorticoid receptors, which interact with DNA….
ISOLATED HYPOALDOSTERONISM
ISOLATED HYPOALDOSTERONISM Part of “CHAPTER 81 – HYPOALDOSTERONISM“ Isolated hypoaldosteronism, a selective deficiency of aldosterone secretion without alteration in cortisol production, results in a persistent hyperkalemia, which may be associated…
BARTTER SYNDROME
BARTTER SYNDROME Part of “CHAPTER 80 – HYPERALDOSTERONISM“ CLINICAL FEATURES AND PATHOPHYSIOLOGY Bartter syndrome includes a number of disorders of tubular transport that may be familial or acquired as a…
SECONDARY HYPERALDOSTERONISM
SECONDARY HYPERALDOSTERONISM Part of “CHAPTER 80 – HYPERALDOSTERONISM“ A variety of disorders of the kidney, heart, liver, and gastrointestinal tract may lead to hyperreninemia and, in turn, to hyperaldosteronism and…
SYNDROMES OF REAL OR APPARENT MINERALOCORTICOID EXCESS NOT CAUSED BY ALDOSTERONE
SYNDROMES OF REAL OR APPARENT MINERALOCORTICOID EXCESS NOT CAUSED BY ALDOSTERONE Part of “CHAPTER 80 – HYPERALDOSTERONISM“ CLINICAL FEATURES AND PATHOPHYSIOLOGY Occasionally, patients may have features of mineralocorticoid excess (hypokalemic…
ADRENOCORTICAL CARCINOMA
ADRENOCORTICAL CARCINOMA Part of “CHAPTER 80 – HYPERALDOSTERONISM“ CLINICAL FEATURES AND PATHOPHYSIOLOGY Adrenocortical carcinoma is an extremely rare cause of hyperal-dosteronism and accounts for fewer than 2% of aldosterone-producing tumors.52,52a…
DEXAMETHASONE-SUPPRESSIBLE HYPERALDOSTERONISM
DEXAMETHASONE-SUPPRESSIBLE HYPERALDOSTERONISM Part of “CHAPTER 80 – HYPERALDOSTERONISM“ CLINICAL FEATURES AND PATHOPHYSIOLOGY Dexamethasone-suppressible hyperaldosteronism (glucocorticoid-remediable aldosteronism) is a rare familial disorder inherited as an autosomal-dominant trait that exhibits the clinical…
