Fig. 10.1 Correlation of EGFR mutations and predicted TKI response Next-Generation Sequencing (NGS) Background The clinical use of NGS has significant benefits for diagnostic biomarker discovery and clinical screening capacity compared…
Method Sensitivity (% mutant DNA) Application Low sensitivity Sanger sequencing 20% Tumor tissue Medium sensitivity Pyro-sequencing 5–10% Tumor tissue TaqMan PCR 5–10% Tumor tissue SNAPSHOT 5–10% Tumor tissue…
© Springer International Publishing AG 2018Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier and Eric H. Bernicker (eds.)Precision Molecular Pathology of Lung CancerMolecular Pathology Libraryhttps://doi.org/10.1007/978-3-319-62941-4_3…
© Springer International Publishing AG 2018Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier and Eric H. Bernicker (eds.)Precision Molecular Pathology of Lung CancerMolecular Pathology Libraryhttps://doi.org/10.1007/978-3-319-62941-4_1…
© Springer International Publishing AG 2018Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier and Eric H. Bernicker (eds.)Precision Molecular Pathology of Lung CancerMolecular Pathology Libraryhttps://doi.org/10.1007/978-3-319-62941-4_2…
© Springer International Publishing AG 2018Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier and Eric H. Bernicker (eds.)Precision Molecular Pathology of Lung CancerMolecular Pathology Libraryhttps://doi.org/10.1007/978-3-319-62941-4_4…
Fig. 1.1 MRI of pelvis (sagittal, T2 sequence), male, ulcerated tumor in the posterior, lower rectum (arrow) Fig. 1.2 Rectal anatomy , lateral view Fig. 1.3 Rectal anatomy , AP…
Fig. 13.1 Lymphatic flow of the rectum. The rectal lymphatic flow is categorized into three categories including an upward lymphatic flow, which moves upward in line with the inferior mesenteric…
Fig. 12.1 Types of intersphincteric resection (ISR) . (a) Partial ISR, (b) subtotal ISR, (c) total ISR, (d) ISR in combination with resection of deep or superficial external anal sphincter…
Fig. 3.1 Axial image showing the difference between a high resolution (left) and lower resolution scan in the same patient (right). The polypoidal tumour is much more clearly depicted on…
