Myeloproliferative Neoplasms

Sep 20, 2016 by in HEMATOLOGY Comments Off on Myeloproliferative Neoplasms

World Health Organization classification for myeloproliferative neoplasms 2008 Chronic myelogenous leukemia Polycythemia vera Essential thrombocythemia Primary myelofibrosis Chronic neutrophilic leukemia Chronic eosinophilic leukemia, not otherwise specified Hypereosinophilic syndrome Mast cell…

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Nursing Issues

Sep 20, 2016 by in HEMATOLOGY Comments Off on Nursing Issues

  Signs and symptoms Nursing management Anaemia Palpitations Red blood cell transfusions Chest pain Administration of erythropoietin agents Fatigue Dyspnea Dizziness Headaches Neutropenia Fever Timely recognition of infection Cough Administration…

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Chronic Myelogeneous Leukemia

Sep 20, 2016 by in HEMATOLOGY Comments Off on Chronic Myelogeneous Leukemia

with indication of high risk by a score >87 and low risk by a score ≤87. Indirectly, the analysis proved that advanced age did not represent an adverse prognostic factor…

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Diffuse Large B-Cell Non-Hodgkin’s Lymphoma (DLBCL- NHL)

Sep 20, 2016 by in HEMATOLOGY Comments Off on Diffuse Large B-Cell Non-Hodgkin’s Lymphoma (DLBCL- NHL)

(a) Diffuse large B-cell lymphoma (DLBCL), NOS T-cell/histiocyte rich large B-cell lymphoma (T/HRBCL) EBV + DLBCL of the “elderly” (b) DLBCL with a predominant extranodal location Primary mediastinal (thymic) large B cell…

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Multiple Myeloma

Sep 20, 2016 by in HEMATOLOGY Comments Off on Multiple Myeloma

Adverse event Novel agent Action Dose-reductions Neutropenia Lenalidomide, Bortezomib G-CSF until neutrophil recovery in case of uncomplicated grade 4 or grade 2–3 complicated by fever or infection. 25–50 % drug…

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Indolent Lymphomas in Older Patients

Sep 20, 2016 by in HEMATOLOGY Comments Off on Indolent Lymphomas in Older Patients

Small lymphocytic lymphoma/ chronic lymphocytic leukemia B-cell prolymphocytic leukemia Splenic marginal zone lymphoma Hairy cell leukemia Splenic B–cell lymphoma/leukemia unclassifiable a Splenic red pulp small B–cell lymphoma a Hairy cell…

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Chronic Lymphocytic Leukemia (CLL)

Sep 20, 2016 by in HEMATOLOGY Comments Off on Chronic Lymphocytic Leukemia (CLL)

Fig. 7.1 Age-distribution among patients with newly diagnosed CLL Biology and Aging The etiology of CLL is unknown and its pathogenesis is not fully understood [2]. The reason why CLL…

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Antibacterial Agents

Sep 20, 2016 by in HEMATOLOGY Comments Off on Antibacterial Agents

Dosing regimen Duration of infusion (h) MIC (μg/mL) Probability of patients achieving a target T > MIC of 30 % 35 % 40 % 45 % 500 mg every 8…

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Central Nervous System Infections

Sep 20, 2016 by in HEMATOLOGY Comments Off on Central Nervous System Infections

Fig. 13.1 Algorithm to diagnose and to treat empirically/preemptively CNS infections in hematology patients Lumbar puncture and cerebrospinal fluid (CSF) analysis should follow the algorithm in Fig. 13.1 and are…

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