Geriatric Assessment
Component Reason for assessment Elements for assessment Method of evaluation Function Functional status measures how independent a patient is and is a key factor for determining treatment success or failure…
Supportive Care in Older Patients with Hematological Malignancies
High (emesis risk >90 % without antiemetics) Carmustine, BCNU Lomustine Cisplatin Mechlorethamine Cyclophosphamide (>1,500 mg/m2) Pentostatin Dacarbazine, DTIC Procarbazine Moderate (emesis risk 30–90 % without antiemetics) Azacytidine Doxorubicin Alemtuzumab Imatinib…
The Challenge of Treating Elderly Patients with Mantle Cell Lymphoma
Points Age (years) ECOG performance status LDH/ULN Leukocytes (×109/L) 0 <50 0–1 <0.670 6,700 1 50–59 – 0.670–0.999 6,700–9,999 2 60–69 2–4 1.000–1.499 10,000–14,999 3 >69 – >1.499 >14,999 Risk…
Acute Myeloid Leukemia
Fig. 4.1 SEER relative survival rates for AML by age group, 1988–2008. SEER surveillance end epidemiology and end results. http://seer.cancer.gov Fig. 4.2 SEER relative survival rates for AML by age…
Myelodysplastic Syndromes in Older Patients
Refractory cytopenias with unilineage dysplasia (RCUD) Refractory anemia (RA) Refractory neutropenia (RN) Refractory thrombocytopenia (RT) Refractory anemia with ring sideroblasts (RARS, ≥15 % BM ringed sideroblasts) Refractory cytopenia with multilineage…
Anemia, Fatigue and Aging
NHANES III [1] Olmsted county [4] Biella [5] Chicago [6] Iron deficiency 16 % 15 % 16 % 25 % Anemia of Chronic Inflammation (ACI) 33.6 % 36 %…
Palliative Care in Elderly Patients with Hematological Malignancies
Diagnosis Median age % of patients dying Place of death In hospital Home Nursing home Hospice MM 73.0 63.4 64.5 15.7 12.0 7.8 DLBCL 70.4 51.8 64.5 14.7 11.3 9.6…
General Considerations on Treatment in Older Patients with Hematological Malignancies
In a series of 400 patients older than 70 with cancer, Luciani et al. [37] studied the SOF (Study of Osteoporotic Fractures) index versus geriatric assessment including 7 questionnaires. Geriatric…
Patients Reported Outcome/Quality of Life
© Springer-Verlag London 2015Ulrich Wedding and Riccardo A. Audisio (eds.)Management of Hematological Cancer in Older People10.1007/978-1-4471-2837-3_18 18. Patients Reported Outcome/Quality of Life Barbara Deschler1, 2 (1) Interdisciplinary Clinical Trials Office, Comprehensive Cancer Center Mainfranken, University Hospital…
Hodgkin Lymphoma in the Elderly
Year Author Number Median age Treatment Outcome Therapy associated death rate Comment 1994 Levis et al. [27] 65 72 years ABVD; MOPP/ABVD CR 67 % 8 year OS 46 %…
