Fig. 1 Impact of efficacy randomized controlled trials on the surgical management of breast cancer (select trials represented) However, even as we acknowledge the important role of RCTs in defining the…
Biology Depth Patient Ulceration Positive deep margin Excessive anxiety Lymphovascular invasion Regression Age (younger) Mitotic rate Clark level IV or V Vertical growth phase >0.75 mm Studies have reported an increased…
Fig. 1 Comparative effectiveness topics 1.1 Prostate Cancer Screening Prostate cancer screening is highly controversial. The United States Preventative Services task force gave prostate cancer screening with PSA a D rating…
Trial N Histology (%) CRT regimen (Gy) Median survival 3 year OS (%) p value Lee et al. [20] 50 S SqCC 100 Cisplatin, 5FU, 45.6 27.3 m – NS 51 CRT…
29. Sinclair CF, McColloch NL, Carroll WR et al (2011) Patient-perceived and objective functional outcomes following transoral robotic surgery for early oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 137:1112–1116CrossRefPubMed 30….
Fig. 1 Pancreas cancer research framework 1.1 Cancer Directed Care Cancer directed care concerns issues of cancer detection, tumor factors, tumor targeted treatments, and subsequent cancer care. Cancer detection involves topics…
Fig. 1 Non-disease factors that influence receipt of lung cancer treatment Limited disease is treated with chemotherapy and radiation therapy, while extensive disease is often treated with chemotherapy. Five-year survival rates…
Fig. 1 The central compartment of the neck (reprinted with permission from Carty et al.) [10] The American Thyroid Association (ATA) defines central compartment neck dissection (CCND) as “the comprehensive, compartment-oriented…
Outcome Clinical area Local recurrence/overall survival Quality of life Cost Multidisciplinary consultation ? NA ? Guideline oriented care ? NA Lower Regionalization of sarcoma care Improved Improved ? Soft…
© Springer International Publishing Switzerland 2015Karl Y. Bilimoria, Christina A. Minami and David M. Mahvi (eds.)Comparative Effectiveness in Surgical OncologyCancer Treatment and Research16410.1007/978-3-319-12553-4_1 Approaches to Answering Critical CER Questions Christine V. Kinnier1, Jeanette W. Chung2 and Karl Y. Bilimoria3 (1) Department…
