Hematologic Emergencies
Adverse outcome predictor Outcome point score Age in years 1 per year Male sex +10 Cancer +30 Heart failure +10 Chronic lung disease +10 Heart rate ≥110 bpm +20 Systolic…
Gastrointestinal Emergencies in the Oncology Patient
© Springer Science+Business Media New York 2016Ellen F. Manzullo, Carmen Esther Gonzalez, Carmen P. Escalante and Sai-Ching J. Yeung (eds.)Oncologic EmergenciesMD Anderson Cancer Care Series10.1007/978-1-4939-3188-0_5 5. Gastrointestinal Emergencies in the Oncology Patient Maria-Claudia Campagna1 , Marina George2, Josiah Halm1 and Asifa Malik3…
Cancer Care Ethics in the Emergency Center
1. The patient’s self-report of pain is a critical component of a comprehensive pain assessment. 2. Optimal pain treatment may be enhanced by acknowledging cultural differences in the expression of…
Nephro-Urologic Emergencies in Patients with Cancer
Prerenal azotemia Volume depletion Nausea, vomiting, diarrhea Decreased oral intake owing to mucositis (5-fluorouracil, methotrexate, taxanes) Polyuria caused by hyperglycemia (steroids) or diabetes insipidus (pituitary tumor) “Third spacing” (hypoalbuminemia, liver…
Rheumatologic/Orthopedic Emergencies
© Springer Science+Business Media New York 2016Ellen F. Manzullo, Carmen Esther Gonzalez, Carmen P. Escalante and Sai-Ching J. Yeung (eds.)Oncologic EmergenciesMD Anderson Cancer Care Series10.1007/978-1-4939-3188-0_7 7. Rheumatologic/Orthopedic Emergencies Huifang Lu1 and Maria E. Suarez-Almazor1 (1) Department of General Internal Medicine,…
Soft Tissue Tumors
Fig. 13.1 Adult-type fibrosarcoma. Fibrosarcoma has evolved from among the most common diagnoses among soft tissue sarcomas to a diagnosis of rigorous exclusion. The morphology depicted, that of a “herringbone”…
Molecular Oncologic Testing of Skin and Adnexa Tumors
Genetic mutation Mutation type Melanoma subtypes affected Melanocytic nevus subtypes affected Type of test KIT Point mutation, amplification Acral (~15 %), Mucosal (~15 %), CSD skin (~10–15 %) Uncommon/rare IHC…
Gastrointestinal and Pancreatobiliary Tumors
Fig. 12.1 Age-standardized colorectal cancer incidence rates by World Health Organization region and sex for 2008 [4] Mortality rates in the United States have declined since the mid-1980s, due to…
Lung and Mediastinal Tumors
Gene Alteration Frequency (%) Histology Smoking history frequent patterns EGFR Mutation 10–35 Adenocarcinoma, few adenosquamous carcinoma Frequent in never smokers KRAS Mutation 15–25 Mostly in adenocarcinomas, frequently mucinous morphology Former/current…
Central Nervous System Tumors
Example clinical reporting—MGMT Negative result RESULT: Gene Methylation NOT detected Positive result RESULT: Gene Methylation DETECTED Methylation of the MGMT (0 (6)–methylguanine–DNA methyltransferase) gene was detected using methylation specific PCR…
