PCOS and Insulin Resistance (IR): From Lifestyle to Insulin Sensitizers
62. Franks S, Kiddy D, Sharp P (1991) Obesity and polycystic ovary syndrome. Ann N Y Acad Sci 626:201–206PubMedCrossRef 63. Holte J, Bergh T, Gennarelli G, Wide L (1994) The…
Prevention of Adolescent Pregnancies
Hormonal Nonhormonal COCs The condom Emergency contraception The double dutch method (COCs and condom) LARCs Othersa Injectable contraception Sponge and diaphragm IUDs Abstinence Implants Withdrawal Patches Periodic sexual intercourse Vaginal…
Validation of Vacuum Sealed, Formalin-Free Tissue Preservation, and Transport System
Fig. 1 Validation trial #1 main hospital specimens Fig. 2 TissueSAFE histologic assessment of morphologic preservation 2 Validation Trial #2—Defining the Transport System from Community Hospital One of our chief goals was…
the Lean lab: The Industry Challenge
The same lack of technical improvements applies to various different steps along the histopathological processing. Tissue fixation is still conducted manually and with the use of formaldehyde originally proposed by…
Marrow Work-up: Report of a Pilot Study
Fig. 1 Morphological evaluation of two differently processed parts of a bone marrow trephine biopsy (H&E). a, c Fixation in 10 % neutral buffered formalin (NBF) at room temperature (RT) for at…
Formalin Fixation Preserves Activation States Efficiently
Fig. 1 ×200 image of a 4-mm-thick human tonsil section placed directly into 40 °C 10 % neutral buffered formalin for 1 h. Sample is stained with hematoxylin and eosin to reveal tissue morphology…
Processing of Native Tissue in Breast Pathology
Indications and contraindications for a frozen section in mammapathology Applicable Non-applicable Clarification of dignity in preoperative uncertain situations (e.g., multicentricity) + Clarification of representativeness (dense breast parenchyma, dislocation of wire…
Formalin Fixation and Rapid Microwave Processing Do Not Affect HER2 Testing
Rapid MW protocol logos™ (1 h 39 min) Reagent Time Phase T °C Pressure (mBar) Formalin 10 % NBF 25′ 1 = 10′ 50° 2 = 15′ Ethanol 60° 2′ Ethanol 99° 3′ Ethanol 99° 16′ 1 = 8′ 65° …
Pre-analytical Phase in Surgical Pathology
Fig. 1 Sequence of the pre-analytical steps. From the surgical theaters, tissue specimens are transferred to Pathological Anatomy. Grossing is immediately followed by fixation and paraffin embedding. After sectioning of the…
in Lung Cancer
Tumor location Method Material Central tumor with bronchial contact Bronchoscopy Conventional bronchial biopsy Bronchial cryobiopsy Brush cytology Bronchoalveolar lavage Peripheral tumor Bronchoscopy Transbronchial biopsy Transbronchial cryobiopsy Transbronchial needle aspiration Brush…
