PK parameter Dimension Relevance t 1/2zp Time Transfer from blood to deep compartment t 1/2el Time Elimination half-life from the body c max Concentration/volume Peak concentration in blood or tissue…
Model Lung unilateral embolization with DSM ± carboDDP, rats: study of pulmonary microcirculation by measurement of FITC-labeled erythrocytes N 12 (2 × 6) Objective Pulmonary microcirculation Comparisons 1. unilateral embolization with DSM 2. unilateral…
Author Method Patients (n) Tumor size (cm) Overall survival p 1 y (%) 3 y (%) 5 y (%) Vivarelli (2004) [17] Surgery 79 n.a. 83 65 n.a. 0.002 RFA…
Concept Resection + intra-arterial chemotherapy vs. resection alone N 51 Access Catheter via A. femoralis in truncus coeliacus Therapy d1: 10 mg/m2 mitoxantrone (over 1 h) d2–4: 170 mg/m2 FA (over 10…
Concept TACE of advanced liver metastases of neuroendocrine tumors (retrospective analysis) N 26 (10× carcinoid syndrome, 2× midgut tumors, 7× pancreatic tumors, 2× malignant insulinomas, 1× stomach carcinoid, 4× CUP)…
Concept Adjuvant HAI after resection of colorectal liver metastases (randomized comparison of HAI + IV vs. IV) N 156 Inclusion criteria R0 resection Therapy 1. (HAI + IV): IV: 325 mg/m2 5FU d1–5 (bolus) + 200…
Fig. 3.1 Normal CT anatomy of the hypopharynx and cervical esophagus. (a) Contrast-enhanced axial CT image obtained at the level of the hypopharynx. The ossified cricoid cartilage (Cr) is identified…
Fig. 2.1 Classification of the depth of invasion 2.2 Macroscopic Features 2.2.1 Handling of Specimens The proper handling of a specimen by a competent pathologist is the most important step…
Fig. 5.1 History of TNM Classification of Malignant Tumours, AJCC Cancer Staging Manual and Japanese Classification of Esophageal Cancer, TNS* Tumor Nomenclature and Statistics, CSCAS* Clinical Stage Classification and Applied…
Fig. 6.1 Encryption with a hash function The patient data were divided into personal data (name, date of birth, medical record number, etc.) and disease data (tumor location, T-factor, N-factor,…
