1 No uptake 2 Uptake ≤ mediastinum 3 Uptake > mediastinum but ≤ liver 4 Uptake moderately higher than liver 5 Uptake markedly higher than liver and/or new lesions X New areas of uptake unlikely to…
Fig. 1 The histopathology of PTLD. a Infectious mononucleosis-like “early” PTLD lesion. b Monomorphic PTLD, Burkitt lymphoma type. c Polymorphic PTLD. d Positive EBV in situ hybridization stain in a PTLD…
Site Procedure Gastric MALT lymphoma Stomach • Endoscopic ultrasound • H. pylori status (by IHC)a • FISH or molecular assay for the t(11;18) translocation Non-gastric MALT lymphoma Breast • Mammography…
Clinical Stage Absolute lymphocyte count Lymphocyte doubling time Bone marrow infiltration pattern Treatment response Age Performance status Genetic IGHV mutational status FISH Low risk: del(13q) Intermediate risk: trisomy 12 High…
© Springer International Publishing Switzerland 2015Andrew M. Evens and Kristie A. Blum (eds.)Non-Hodgkin LymphomaCancer Treatment and Research16510.1007/978-3-319-13150-4_14 Allogeneic Hematopoietic Cell Transplantation in Non-Hodgkin’s Lymphomas Ibrahim Aldoss1 and Auayporn Nademanee1 (1) City of Hope National Medical Center,…
T-cell prolymphocytic leukemia T-cell large granular lymphocytic leukemia Chronic lymphoproliferative disorder of NK cell Aggressive NK leukemia Systemic EBV-positive T-cell lymphoproliferative disorder of childhood Hydroa vaccineforme-like lymphoma Adult T-cell leukemia/lymphoma…
Fig. 1 Our approach to MCL treatment Table 1 Frontline regimens in patients ≤70 years Frontline regimen Age (years) ORR (%) PFS/FFS OS R-Hyper-CVAD [16] ≤81 97 3 years 64 % (≤65 3 years 73 %)…
Expected immunophenotype Follicular lymphoma CD19+, CD20+, IgM ± IgD, monotypic sIg+, CD10+, bcl-6+, bcl-2 ±, HGAL, LMO2; associated with CD21+/CD23+ follicular dendritic cell meshworks Lymphoplasmacytic lymphoma CD19+, CD20+, monotypic sIg+, IgM, CD22+,…
IgG IgA IgM IgD IgE Heavy chain Classes Gamma (γ) Alpha (α) Mu (μ) Delta (δ) Epsilon (ε) Subclasses IgG1, IgG2, IgG3, IgG4 IgA1, IgA2 None None None Light…
Fig. 7.1 Peripheral blood film showing typical CLL cells and a smear cell (1,000× magnification) Fig. 7.2 Peripheral blood film showing prolymphocytes along with typical CLL cells (1,000× magnification) In…
