Central Precocious Puberty: From Diagnosis to Treatment
Cause Symptoms and signs Evaluation Due to a CNS lesion Hypothalamic hamartoma May be associated with gelastic (laughing attacks), focal or tonic-clonic seizures. MRI: Mass in the floor of…
SGLT2 Inhibitors for Treating Diabetes
and Rachel Livingstone2 (1) Glasgow Royal Infirmary, Glasgow, UK (2) Specialty Trainee, Royal Alexandria Hospital, Paisley, UK 2.1 Mode of Action and Clinical Pharmacology Sodium-glucose cotransporter-2 (SGLT2) inhibitors have a…
Guidelines for the Treatment of Type 2 Diabetes Mellitus
(1) Glasgow Royal Infirmary, Glasgow, UK 3.1 Introduction Evidence-based clinical practice guidelines are systematically developed statements intended to assist practitioners and patients about making and understanding care decisions for…
Overview of Type 2 Diabetes
Figure 1.1 Global prevalence of diabetes (Reproduced with permission from the International Diabetes Federation [1] ©IDF) 1.2 Diagnostic Criteria for Diabetes The diagnostic criteria from the World Health Organization (WHO)…
Using SGLT2 Inhibitors in Special Populations
(1) Glasgow Royal Infirmary, Glasgow, UK 4.1 Introduction Type 2 diabetes is becoming a common problem in young obese people and, in some parts of the world, is as…
Ovarian Endocrinology
Fig. 1.1 Schematic of GnRH synthesis. A, Representation of prepro-GnRH, including a 23-amino acid signal sequence, GnRH, a proteolytic processing site (Gly-Lys-Arg), and GnRH-associated peptide (GAP). The arrow indicates the site…
Immature Oocyte Retrieval for IVM Treatment
Fig. 24.1 IVM protocols at IVF Osaka Clinic. Fresh or frozen IVM are applied depending on the thickness of endometrium on the day of HCG administration Appropriate Timing for Retrieval Although…
Cumulative Pregnancy Rates After Six Cycles of Modified Natural Cycle IVF
Fig. 13.1 Number of patients undergoing MNC-IVF and number of cycles performed Fig. 13.2 Cumulative pregnancy rates per patient In this chapter, results of our original studies and cumulative pregnancy rates after…
Mild Stimulation Protocols: Combination of Clomiphene Citrate and Recombinant FSH or HMG
Fig. 15.1 Forest plot of comparison: 1 Clomiphene citrate with gonadotropins (with or without mid-cycle antagonist) versus gonadotropins with GnRH agonists protocols in IVF and ICSI cycles, outcome: 1.1 live birth…
Minimally Invasive IVF as an Alternative Treatment of Option for Infertility Couples: (INVO) Procedure
Fig. 19.1 INVO principle. INVOcell device is permeable to CO2 gas and allows the equilibrium between the pCO2 of the vaginal/rectal venous plexus (~5–6%) and the pCO2 of the culture medium…
